Detail publikace

Influence of ischemia on left ventricular depolarization in isolated rabbit hearts perfused according to Langendorff

KOLÁŘOVÁ, J. JANOUŠEK, O. NOVÁKOVÁ, M. FIALOVÁ, K. PROVAZNÍK, I.

Originální název

Influence of ischemia on left ventricular depolarization in isolated rabbit hearts perfused according to Langendorff

Český název

Influence of ischemia on left ventricular depolarization in isolated rabbit hearts perfused according to Langendorff

Typ

článek ve sborníku ve WoS nebo Scopus

Jazyk

cs

Originální abstrakt

The aim of this study was to search for relation between electrical activity recorded from whole isolated heart and simultaneously from one cell. The QRS complex of elec-trogram (ECG) corresponds to the depolarization of the ven-tricles. The depolarization propagation is shown by monopha-sic action potential (MAP) recorded at appointed place during experiment. Electrogram changes observed during ischemia should be accounted for changes on cellular level. MAPs and ECG were recorded simultaneously. The activation time (AT), defined as distance from the earliest QRS deflection to MAP upstroke, changes with duration of ischemia. The excitement propagation and conduction in ischemic heart takes longer time in comparison to non-ischemic myocardium.

Český abstrakt

The aim of this study was to search for relation between electrical activity recorded from whole isolated heart and simultaneously from one cell. The QRS complex of elec-trogram (ECG) corresponds to the depolarization of the ven-tricles. The depolarization propagation is shown by monopha-sic action potential (MAP) recorded at appointed place during experiment. Electrogram changes observed during ischemia should be accounted for changes on cellular level. MAPs and ECG were recorded simultaneously. The activation time (AT), defined as distance from the earliest QRS deflection to MAP upstroke, changes with duration of ischemia. The excitement propagation and conduction in ischemic heart takes longer time in comparison to non-ischemic myocardium.

Klíčová slova

Electrogram, monophasic action potential, activation time, ischemia, reperfusion, isolated rabbit heart.

Rok RIV

2009

Vydáno

07.09.2009

Nakladatel

Springer Berlin

Místo

Munich, Germany

ISBN

978-3-642-03897-6

Kniha

IFMBE Proceeding, Volume 25, World Congress on Medical Physics and Biomedical Engineering

Strany od

1419

Strany do

1422

Strany počet

4

BibTex


@inproceedings{BUT31338,
  author="Jana {Kolářová} and Oto {Janoušek} and Marie {Nováková} and Kateřina {Fialová} and Ivo {Provazník}",
  title="Influence of ischemia on left ventricular depolarization in isolated rabbit hearts perfused according to Langendorff",
  annote="The aim of this study was to search for relation between electrical activity recorded from whole isolated heart and simultaneously from one cell. The QRS complex of elec-trogram (ECG) corresponds to the depolarization of the ven-tricles. The depolarization propagation is shown by monopha-sic action potential (MAP) recorded at appointed place during experiment. Electrogram changes observed during ischemia should be accounted for changes on cellular level. MAPs and ECG were recorded simultaneously. The activation time (AT), defined as distance from the earliest QRS deflection to MAP upstroke, changes with duration of ischemia. The excitement propagation and conduction in ischemic heart takes longer time in comparison to non-ischemic myocardium.",
  address="Springer Berlin",
  booktitle="IFMBE Proceeding, Volume 25, World Congress on Medical Physics and Biomedical Engineering",
  chapter="31338",
  howpublished="print",
  institution="Springer Berlin",
  year="2009",
  month="september",
  pages="1419--1422",
  publisher="Springer Berlin",
  type="conference paper"
}