Publication detail

Comparison of ASL and DCE-MRI Perfusion Map in Small Animal Model of Cancer

GROSSOVÁ, L. JIŘÍK, R. SOUČEK, K. DRAŽANOVÁ, E. STARČUK, Z.

Original Title

Comparison of ASL and DCE-MRI Perfusion Map in Small Animal Model of Cancer

English Title

Comparison of ASL and DCE-MRI Perfusion Map in Small Animal Model of Cancer

Type

conference paper

Language

en

Original Abstract

This paper is focused on quantitative perfusion analysis using pulsed ASL (FAIRRARE) and DCE-MRI (using high- and low-molecular-weight contrast agents) in a mouse tumour model. Tumour blood-flow maps of both methods were compared using visual assessment, region analysis (median, percentiles), scatter plots and correlation coefficients. ASL blood-flow estimates matched the DCE-MRI blood-flow estimations in some cases. Possible reasons for poor match in the other cases were investigated. This study indicates that in tumour perfusion analysis, we might profit from the combination of ASL and DCEMRI instead of using just one of them.

English abstract

This paper is focused on quantitative perfusion analysis using pulsed ASL (FAIRRARE) and DCE-MRI (using high- and low-molecular-weight contrast agents) in a mouse tumour model. Tumour blood-flow maps of both methods were compared using visual assessment, region analysis (median, percentiles), scatter plots and correlation coefficients. ASL blood-flow estimates matched the DCE-MRI blood-flow estimations in some cases. Possible reasons for poor match in the other cases were investigated. This study indicates that in tumour perfusion analysis, we might profit from the combination of ASL and DCEMRI instead of using just one of them.

Keywords

Blood Flow Quantification, ASL, DCE-MRI, Perfusion, Tumour

RIV year

2015

Released

25.05.2015

ISBN

978-80-969672-9-2

Book

10th International Conference on Measurement

Pages from

160

Pages to

163

Pages count

4

BibTex


@inproceedings{BUT117240,
  author="Lucie {Krátká} and Radovan {Jiřík} and Karel {Souček} and Eva {Dražanová} and Zenon {Starčuk}",
  title="Comparison of ASL and DCE-MRI Perfusion Map in Small Animal Model of Cancer",
  annote="This paper is focused on quantitative perfusion analysis using pulsed ASL (FAIRRARE)
and DCE-MRI (using high- and low-molecular-weight contrast agents) in a mouse
tumour model. Tumour blood-flow maps of both methods were compared using visual
assessment, region analysis (median, percentiles), scatter plots and correlation coefficients.
ASL blood-flow estimates matched the DCE-MRI blood-flow estimations in some cases.
Possible reasons for poor match in the other cases were investigated. This study indicates
that in tumour perfusion analysis, we might profit from the combination of ASL and DCEMRI
instead of using just one of them.",
  booktitle="10th International Conference on Measurement",
  chapter="117240",
  howpublished="print",
  year="2015",
  month="may",
  pages="160--163",
  type="conference paper"
}