Detail publikace

ECG Segment Variability During Voltage Sensitive Dye Application in Animal Heart

Originální název

ECG Segment Variability During Voltage Sensitive Dye Application in Animal Heart

Anglický název

ECG Segment Variability During Voltage Sensitive Dye Application in Animal Heart

Jazyk

en

Originální abstrakt

The optical mapping of action potentials from heart surface is extensively used as a new possibility of non-invasive recording methods. It employs application of voltage-sensitive dyes (VSDs). Previously, VSDs has been successfully used in myocardial ischemia studies. Our previous Langendorff perfused heart experiments that have suggested shape changes in ECG signals in time and time-frequency domain caused by application of VSD di-4-ANEPPS during optical mapping. These changes went through detailed analysis to reveal impact to particular fractions of a heart cycle. The heart cycle was divided into three parts, corresponded to P-Q segments, QRS complexes, and ST-T segments. Dynamic time warping (DTW) is applied to all marked segments in each experimental period (control, loading and washout phase). Variability of ECG parts is measured by means of an optimal path resulting from DTW based on minimum distance between the control signal segments (before the application of VSD) and segments recorded in next two experimental steps.

Anglický abstrakt

The optical mapping of action potentials from heart surface is extensively used as a new possibility of non-invasive recording methods. It employs application of voltage-sensitive dyes (VSDs). Previously, VSDs has been successfully used in myocardial ischemia studies. Our previous Langendorff perfused heart experiments that have suggested shape changes in ECG signals in time and time-frequency domain caused by application of VSD di-4-ANEPPS during optical mapping. These changes went through detailed analysis to reveal impact to particular fractions of a heart cycle. The heart cycle was divided into three parts, corresponded to P-Q segments, QRS complexes, and ST-T segments. Dynamic time warping (DTW) is applied to all marked segments in each experimental period (control, loading and washout phase). Variability of ECG parts is measured by means of an optimal path resulting from DTW based on minimum distance between the control signal segments (before the application of VSD) and segments recorded in next two experimental steps.

BibTex


@article{BUT46327,
  author="Jana {Kolářová} and Marek {Vyklický} and Ivo {Provazník} and Marie {Nováková}",
  title="ECG Segment Variability During Voltage Sensitive Dye Application in Animal Heart",
  annote="The optical mapping of action potentials from heart surface is extensively used as a new possibility of non-invasive recording methods. It employs application of voltage-sensitive dyes (VSDs). Previously, VSDs has been successfully used in myocardial ischemia studies. Our previous Langendorff perfused heart experiments that have suggested shape changes in ECG signals in time and time-frequency domain caused by application of VSD di-4-ANEPPS during optical mapping. These changes went through detailed analysis to reveal impact to particular fractions of a heart cycle. The heart cycle was divided into three parts, corresponded to P-Q segments, QRS complexes, and ST-T segments. Dynamic time warping (DTW) is applied to all marked segments in each experimental period (control, loading and washout phase). Variability of ECG parts is measured by means of an optimal path resulting from DTW based on minimum distance between the control signal segments (before the application of VSD) and segments recorded in next two experimental steps.",
  chapter="46327",
  journal="Scripta medica",
  number="6",
  volume="78",
  year="2005",
  month="december",
  pages="273--279",
  type="journal article - other"
}