Detail publikace

Thin TiO2Coatings by ALD Enhance the Cell Growth on TiO2Nanotubular and Flat Substrates

MOTOLA, M. ČAPEK, J. ZAZPE MENDIOROZ, R. BAČOVÁ, J. HROMÁDKO, L. BRŮČKOVÁ, L. NG, S. HANDL, J. SPOTZ, Z. KNOTEK, P. BAISHYA, K. MAJTNEROVÁ, P. PŘIKRYL, J. SOPHA, H. ROUŠAR, T. MACÁK, J.

Originální název

Thin TiO2Coatings by ALD Enhance the Cell Growth on TiO2Nanotubular and Flat Substrates

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

The present work exploits Ti sheets and TiO2 nanotube (TNT) layers and their surface modifications for the proliferation of different cells. Ti sheets with a native oxide layer, Ti sheets with a crystalline thermal oxide layer, and two kinds of TNT layers (prepared via electrochemical anodization) with a defined inner diameter of 12 and 15 nm were used as substrates. A part of the Ti sheets and the TNT layers was additionally coated by thin TiO2 coatings using atomic layer deposition (ALD). An increase in cell growth of WI-38 fibroblasts (>50%), MG-63 osteoblasts (>30%), and SH-SY5Y neuroblasts (>30%) was observed for all materials coated by five cycles ALD compared to their uncoated counterparts. The additional ALD TiO2 coatings changed the surface composition of all materials but preserved their original structure and protected them from unwanted crystallization and shape changes. The presented approach of mild surface modification by ALD has a significant effect on the materials’ biocompatibility and is promising toward application in implant materials.

Klíčová slova

TiO2 nanotube layers, Ti sheets, atomic layer deposition, coatings, cell growth

Autoři

MOTOLA, M.; ČAPEK, J.; ZAZPE MENDIOROZ, R.; BAČOVÁ, J.; HROMÁDKO, L.; BRŮČKOVÁ, L.; NG, S.; HANDL, J.; SPOTZ, Z.; KNOTEK, P.; BAISHYA, K.; MAJTNEROVÁ, P.; PŘIKRYL, J.; SOPHA, H.; ROUŠAR, T.; MACÁK, J.

Vydáno

21. 9. 2020

Nakladatel

American Chemical Society

ISSN

2576-6422

Periodikum

ACS Applied Bio Materials

Ročník

3

Číslo

9

Stát

Spojené státy americké

Strany od

6447

Strany do

6456

Strany počet

10

URL

https://pubs.acs.org/doi/10.1021/acsabm.0c00871

Plný text v Digitální knihovně

http://hdl.handle.net/11012/196522

BibTex

@article{BUT167263,
  author="Martin {Motola} and Jan {Čapek} and Raúl {Zazpe Mendioroz} and Jana {Bačová} and Luděk {Hromádko} and Lenka {Brůčková} and Siow Woon {Ng} and Jiří {Handl} and Zdeněk {Spotz} and Petr {Knotek} and Kaushik {Baishya} and Pavlína {Majtnerová} and Jan {Přikryl} and Hanna Ingrid {Sopha} and Tomáš {Roušar} and Jan {Macák}",
  title="Thin TiO2Coatings by ALD Enhance the Cell Growth on TiO2Nanotubular and Flat Substrates",
  journal="ACS Applied Bio Materials",
  year="2020",
  volume="3",
  number="9",
  pages="6447--6456",
  doi="10.1021/acsabm.0c00871",
  issn="2576-6422",
  url="https://pubs.acs.org/doi/10.1021/acsabm.0c00871"
}