Detail publikace

Electrochemical Determination of Vitamin D3 in Pharmaceutical Products by Using Boron Doped Diamond Electrode

DUROVIC, A. STOJANOVIC, Z. KRAVIC, S. KOS, J. RICHTERA, L.

Originální název

Electrochemical Determination of Vitamin D3 in Pharmaceutical Products by Using Boron Doped Diamond Electrode

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

A sensitive square-wave voltammetry method was developed to determine cholecalciferol (vitamin D-3) in pharmaceutical products at boron-doped diamond electrode as a working electrode. Vitamin D-3 provided a well-defined voltammetric peak at around +1.00 V (vs. Ag/AgCl, 3.5 mol dm(-3)) in 0.02 mol dm(-3) Britton-Robinson buffer pH 5.0 prepared in 50 % ethanol. The influence of various factors such as type and pH of the supporting electrolyte, scan rate and square-wave parameters were studied and optimized. Under optimum conditions, the oxidation peak current increased linearly with the concentration of vitamin D-3 over the range of 2 to 200 mu mol dm(-3). The calculated limit of detection and limit of quantitation were 0.17 mu mol dm(-3) and 0.51 mu mol dm(-3), respectively. The boron-doped diamond electrode exhibited specific recognition capability for cholecalciferol amongst possible interferences, and the determination of vitamin D-3 was possible in samples such as commercial pharmaceutical products without complicated sample pretreatments.

Klíčová slova

Boron doped diamond electrode; Pharmaceutical samples; Sensors; Vitamin D; Voltammetry

Autoři

DUROVIC, A.; STOJANOVIC, Z.; KRAVIC, S.; KOS, J.; RICHTERA, L.

Vydáno

30. 4. 2020

ISSN

1040-0397

Periodikum

ELECTROANALYSIS

Ročník

32

Číslo

4

Stát

Spolková republika Německo

Strany od

741

Strany do

748

Strany počet

8

URL

https://onlinelibrary.wiley.com/doi/abs/10.1002/elan.201900532

BibTex

@article{BUT161351,
  author="Ana {Durovic} and Zorica {Stojanovic} and Snezana {Kravic} and Jovana {Kos} and Lukáš {Richtera}",
  title="Electrochemical Determination of Vitamin D3 in Pharmaceutical Products by Using Boron Doped Diamond Electrode",
  journal="ELECTROANALYSIS",
  year="2020",
  volume="32",
  number="4",
  pages="741--748",
  doi="10.1002/elan.201900532",
  issn="1040-0397",
  url="https://onlinelibrary.wiley.com/doi/abs/10.1002/elan.201900532"
}