Course detail

Biosensors

FEKT-ABSNAcad. year: 2010/2011

The subject covers a wide spectrum of typical conventional sensors, semiconductor ad optical fibre sensors, sensors of mechanical quantities and biosensors, DNA sensors.

Language of instruction

Czech

Number of ECTS credits

5

Mode of study

Not applicable.

Guarantor

prof. Ing. Radimír Vrba, CSc.

Department

Department of Microelectronics (UMEL)

Learning outcomes of the course unit

A fundamental knowledge of the types and principles of sensors used in medicine, theoretical knowledge and practical experience in sensorics.

Prerequisites

Knowledge at secondary school level and of completed subjects in the study area

Co-requisites

Not applicable.

Planned learning activities and teaching methods

Teaching methods depend on the type of course unit as specified in the article 7 of BUT Rules for Studies and Examinations.

Assesment methods and criteria linked to learning outcomes

Requirements for successful completion of the subject are specified in guarantor‘ s regulation updated for every academic year.

Course curriculum

Covered in detail are sensors used in medicine. Particular emphasis is laid on chemical sensors and biosensors. Fundamental principles and construction of modern microsensors, impact of minituarisation on the parameters of microsensors and their applications.

Work placements

Not applicable.

Aims

To provide the students with an overview of the fundamental physical, chemical and biochemical principles and characteristics of the principal types of sensors for medicine, and for the design of analyzers and other medical devices.

Specification of controlled education, way of implementation and compensation for absences

Extent and forms are specified by guarantor’s regulation updated for every academic year.

Recommended optional programme components

Not applicable.

Prerequisites and corequisites

Not applicable.

Basic literature

Skládal, P.: Biosensory, Masarykova univerzita, Brno 2002 (CS)

Recommended reading

Not applicable.

Classification of course in study plans

  • Programme BTBIO-A Bachelor's

    branch A-BTB , 3. year of study, winter semester, compulsory

  • Programme EEKR-CZV lifelong learning

    branch ET-CZV , 1. year of study, winter semester, compulsory

Type of course unit

 

Lecture

26 hours, optionally

Teacher / Lecturer

prof. Ing. Jaromír Hubálek, Ph.D.

Syllabus

1. Introduction, principal types of chemical sensors and biosensors, definitions, measurement
principle.
2. Electrochemical sensors and microsensors, impedimetric sensors
3. Conductometric chemosensors, conductometric biosensors
4. Potentiometric sensors, amperometric sensors, pH sensors, polarographic sensors
5. Potentiometric biosensors and amperometric biosensors, bioelectrodes
6. Ion selective sensors, ISFET sensors, LAPS biosensors
7. Special electrochemical techniques - voltmetry, chronoamperometry, rotating techniques
8. Calorimetric biosensors, gravimetric chemo- and biosensors and microsensors
9. Temperature and optical chemo- and biosensors and microsensors
10. Fluorescence chemo- and biosensors and microsensors, chemiluminescence, bioluminescence
11. Special biosensosrs, enzyme biosensors, converters for bioaffinite sensors
12. Immunosensors, electrochemical biosensors for DNA
13. Physical sensors – temperature, flow, force, pressure, humidity, magnetic sensors, the Hall effect

Laboratory exercise

26 hours, compulsory

Teacher / Lecturer

Ing. Zdeněk Pytlíček, Ph.D.
Ing. Jiří Sedláček
Ing. Jaromír Žák, Ph.D.

Syllabus

1. Introduction to the measurement basics, measurement devices and laboratory tasks
2. Ultrasonic sensor
3. Detection of gases – O2 a CO2
4. Calorimetric sensor of the flow of fluids
5. Scanning of revolutions by means of the Hall sensor
6. Measurement of heavy metals by the potentiometric method
7. Measurement of pH solutions, conductivity measurement of water solutions
8. Amperometric biosensor
9. Humidity measurement
10. Pressure measurement
11. Lighting measurement
12. Temperature measurement
13. Substitute exercises