Course detail

Materials for Biomedical Applications

FEKT-MMBAAcad. year: 2018/2019

The course deals with materials including nanostructured ones and prepared by special technologies to be applied in biomedical praxis. Further, the action of biological environment on the corrosion and life time of materials used also the compatibility of implants in tissues will be addressed. Metrology of nanostructures such as microscopy, mass spectrometry of secondary ions and/or X-ray analysis will be explained. Recently invented electrochemical power sources designed for applications in medicine such as special diagnostic and therapeutic tools or pacemakers will be involved into a separate chapter. The chapter describing NMR for both diagnostic and analytical purposes will be also significant.

Learning outcomes of the course unit

The graduate after finishing proposed course will have be able following actions:
• Qualified judging of the materials application in biomedical praxis
• Describe the diseases of heart and vessel system and to describe the strategy of their treating
• Describe the properties of macromolecular materials, ceramics and metals suitable for implants
• To have a general survey over recent situation of materials for contact and implanted eye lenses
• To possess fundamental knowledge of usage of electrochemical power sources for laboratory equipment, cardio stimulators /peace makers and defibrillators
• To be informed of the newest trends in preparation and application of bio nanomaterials in medicine, for example, for the treatment of carcinogenous diseases
• To be avare of the nuclear magnetic spectroscopu (NMR) and of the tissues compatibility in NMR diagnostics

Prerequisites

Student who enrols this subject should be able to be able: •to be knowledgeable in fundamental concepts of medicine •to possess fundamental surwey of biochemical processes in living bodies •to be able to explain essentials of elecric circuits used in biomedicine •to be able to safely handle chemicals according to a manual

Co-requisites

Not applicable.

Recommended optional programme components

Not applicable.

Recommended or required reading

Sedlaříková,M. a kol. Materiály pro biomedicínu, elektronická skripta (CS)
Vondrák, J., Sedlaříková,M.,Elektrochemická měření, elektronická verze (CS)
Bednář B. a kol.:Nové materiály, VŠCHT, Praha 1991 (CS)
VONDRÁK, J., SEDLAŘÍKOVÁ, M., REITER, J., NOVÁK, V., NEČESAL, P. Carbon and/ or graphite anodes for gel polymer batteries. In International Meeting on Lithium Batteries. Nara, Japonsko: The Electrochemical Society, Inc., 2004. s. 234 ( s.)ISBN: 1-56677-415- 2. (CS)
Pistoia, G.: Lithium Batteries, New Materials, Developments and Perspective, Elsevier Science B.V., Amsterodam, 1994 (EN)
Valečko,Z: Bioelektronika, BEN Technická literatura, Praha 2005 (CS)
Navrátil,L. a kol: Medicínská biofyzika, GRADA 2005, Praha (CS)
Žabka,M. a kol.:Moderní lékové formy ve farmaceutické technologii, Bratislava 2001 (CS)
Liu,B. In vitro investigation of Fe30Mn6Si shape memory alloy as potential biodegradable metallic material, Material Letters 65 (2011) 540-543 (EN)

Planned learning activities and teaching methods

Techning methods include lectures, practical laboratories and excursion. Course is taking advantage of e-learning (Moodle) system. Students have to write a single project/assignment during the course.

Assesment methods and criteria linked to learning outcomes

Classification of laboratory work ( 6 work assignment )...summary 30p
Written part of closing examen..............................................................60p
Presentation of assignet topic................................................................10p

Language of instruction

Czech

Work placements

Not applicable.

Course curriculum

1. Influence of the structure of atoms and structure on properties of materials
2. Metal materials and their use in biomedicine
3.Corrosion and compatibility of materials in living organisms
4. Polymers and their use in medicine, implants, intraocular and contact lenses
5. Drug forms, targeted cytostatics
6. Influence of ions of various elements on composition and properties
  tissue fluids, health effects
7. Chemical sources of electrical energy and their use in medicine
8. Using modeling and 3D printing in medicine
devices
5. Materials for biological environment
6. Influence of ions and compounds of selected elements on composition
and properties of fluids from tissues
7. Fundamentals of NMR spectroscopy and tomography and basic
diagnostic methods
8. NMR compatibility of implantates in tissues, magnetic susceptibility of
materials

Aims

The proposed subject will prepare the pregraduate students of FEEC for the solution of technological, economic and ecologic problems connected with the choice, usage and testing of various materials in biomedical applications.

Specification of controlled education, way of implementation and compensation for absences

Exercises in laboratory are obligatory. Dully excussed absence in laboratory exercises is possible to complete after being approved by the teacher.

Classification of course in study plans

  • Programme EEKR-M1 Master's

    branch M1-BEI , 1. year of study, summer semester, 5 credits, optional interdisciplinary
    branch M1-EVM , 1. year of study, summer semester, 5 credits, optional specialized

  • Programme EEKR-CZV lifelong learning

    branch ET-CZV , 1. year of study, summer semester, 5 credits, optional specialized

Type of course unit

 

Laboratory exercise

26 hours, compulsory

Teacher / Lecturer