Course detail

Chemometrics

FCH-MC_CHMAcad. year: 2011/2012

Foundations of descriptive statistics. Point and interval estimations of random variables and their properties. Testing of statistical hypotheses, one sample tests, godness of fit tests. Random vectors, simultaneous and marginal distributions, the conditional density and probablistic functions. Numerical characteristics - the concepts of mean value, variance, covariance. Two sample tests. Multivariate normal distribution. The least square method, linear regression model and its generalizations and modifications. Intriduction to the non-linear regression, elements of regression diagnostics. Introduction to the variance analysis - the methods of Tuckey, Bartlett´s test, one and two factor ANOVA tests,The method of Schéffe and its application for determining of confidence zone in the linear regression model. Non-parametric tests - the sign test, Wilcoxon's test and Kruskal- Wallis test. Eigen-values and eigen-vectors, the principal component analysis and its application for data reduction. Foundations of factor analysis and its applications in the living environment research. Introduction to the discriminant analysis and its biomedicine applications. Introduction to the theory of neural nets, an alternative model to the classical statistics methods.

Language of instruction

Czech

Number of ECTS credits

4

Mode of study

Not applicable.

Learning outcomes of the course unit

A student will manage both theoretical and practical knowledge of mathematical statistics and its application in the evaluation of experimental data. He will be able of testing statistical hypotheses, application of regression models and application of more advanced multivariate statistical methods in biomedicine, living environment research, analytical chemistry and and other scientific branches.

Prerequisites

Foundations of mathematical analysis and linear algebra. Foundations of the probability theory and the most common continuous and discrete distributions.

Co-requisites

Not applicable.

Planned learning activities and teaching methods

Lecture.

Assesment methods and criteria linked to learning outcomes

The classification is given by the examination consisting of the test and oral parts.

Course curriculum

1. Foundations of descriptive statistics, Point and interval estimations and their properties.
2. Interval estimations, testing of statistical hypotheses, one sample tests, godness of fit tests.
3. Random vectors, simultaneous and marginal distributions, the conditional density and probablistic functions.
4. Numerical characteristics - the concepts of mean value, variance, covariance and correlation matrices. Multivariate normal distribution.
5. Two sample tests. The least square method and linear regression model, applications.
6. Some generalizations and modifications of the linear regression model, intriduction to the non-linear regression, elements of regression diagnostics.
7. Introduction to the variance analysis - the methods of Tuckey, Bartlett´s test, one and two factor ANOVA tests.
8. The method of Schéffe and its application for determining of confidence zone in the linear regression model. Non-parametric tests - the sign test, Wilcoxon's test and Kruskal- Wallis test. 9. Eigen-values and eigen-vectors, the principal component analysis and its application for data reduction.
10. Foundations of factor analysis and its applications in the living environment research.
11. Introduction to the discriminant analysis and its applications in biomedicine. Introduction to the theory of neural nets - inner potential, organization, active and adaptive dynamics.
12. Perceptron nets and the backpropagation method as a fundamental training method. Logistic regression and its connection with perceptrons, applications in biomedicine.
13. Neural nets as an alternative model to the classical statistics data processing. Information about linear associative nets, hebbian training and its applications in informatics (autoassociative and hetero associative memories).

Work placements

Not applicable.

Aims

The aim of the course is to manage and apply the methods of mathematical staistings for processing of experimental data.

Specification of controlled education, way of implementation and compensation for absences

Participation on lectures is not compulsory. The course is finished by an examination consisting of the test and oral parts.

Recommended optional programme components

Not applicable.

Prerequisites and corequisites

Not applicable.

Basic literature

Not applicable.

Recommended reading

Not applicable.

Classification of course in study plans

  • Programme NKCP_SCH Master's

    branch NKCO_SCH , 1. year of study, summer semester, compulsory-optional

  • Programme NPCP_SCH Master's

    branch NPCO_SCH , 1. year of study, summer semester, compulsory-optional
    branch NPCO_SCH , 2. year of study, summer semester, compulsory-optional

  • Programme NKCP_SCH Master's

    branch NKCO_SCH , 2. year of study, summer semester, compulsory-optional

Type of course unit

 

Lecture

26 hours, optionally

Teacher / Lecturer

Guided consultation in combined form of studies

13 hours, optionally

Teacher / Lecturer