Publication detail

Development of a realistic human airway model

LÍZAL, F. ELCNER, J. HOPKE, P. JEDELSKÝ, J. JÍCHA, M.

Original Title

Development of a realistic human airway model

Type

journal article in Web of Science

Language

English

Original Abstract

Numerous models of human lungs with various levels of idealization have been reported in the literature; consequently, results acquired using these models are difficult to compare to in vivo measurements. We have developed a set of model components based on realistic geometries, which permits the analysis of the effects of subsequent model simplification. A realistic digital upper airway geometry except for the lack of an oral cavity has been created which proved suitable both for computational fluid dynamics (CFD) simulations and for the fabrication of physical models. Subsequently, an oral cavity was added to the tracheobronchial geometry. The airway geometry including the oral cavity was adjusted to enable fabrication of a semi-realistic model. Five physical models were created based on these three digital geometries. Two optically transparent models, one with and one without the oral cavity, were constructed for flow velocity measurements, two realistic segmented models, one with and one without the oral cavity, were constructed for particle deposition measurements, and a semi-realistic model with glass cylindrical airways was developed for optical measurements of flow velocity and in situ particle size measurements. One-dimensional phase doppler anemometry measurements were made and compared to the CFD calculations for this model and good agreement was obtained.

Keywords

Human airway model, tracheo-bronchial tree, particle transport, particle deposition, oral cavity

Authors

LÍZAL, F.; ELCNER, J.; HOPKE, P.; JEDELSKÝ, J.; JÍCHA, M.

RIV year

2012

Released

17. 2. 2012

Publisher

SAGE PUBLICATIONS LTD

Location

London

ISBN

0954-4119

Periodical

PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE

Year of study

226

Number

H3

State

United Kingdom of Great Britain and Northern Ireland

Pages from

197

Pages to

207

Pages count

11

URL

http://pih.sagepub.com/content/early/2011/12/02/0954411911430188

BibTex

@article{BUT76135,
  author="František {Lízal} and Jakub {Elcner} and Philip K. {Hopke} and Jan {Jedelský} and Miroslav {Jícha}",
  title="Development of a realistic human airway model",
  journal="PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE",
  year="2012",
  volume="226",
  number="H3",
  pages="197--207",
  issn="0954-4119",
  url="http://pih.sagepub.com/content/early/2011/12/02/0954411911430188"
}