Publication detail

Fluorescence Spectroscopy Study of Hyaluronan-Phospholipid Interactions

MRAVEC, F. KLUČÁKOVÁ, M. PEKAŘ, M.

Original Title

Fluorescence Spectroscopy Study of Hyaluronan-Phospholipid Interactions

English Title

Fluorescence Spectroscopy Study of Hyaluronan-Phospholipid Interactions

Type

book chapter

Language

en

Original Abstract

Capability of phospholipids with positive charge to form complexes with hyaluronan in aqueous solutions, in a similar way as traditional cationic surfactants, was investigated by fluorescence probes. DPPC and lecithin aggregate in aqueous solution to form micelle-like structures capable to solubilize hydrophobic molecules. Changes in aggregation behavior after adding hyaluronan were observed only in the case of lecithin. Further, non-ionic biocompatible surfactant was used as additional dispersion environment in phospholipid-hyaluronan system with phospholipid molecules acting as a physical linker bonding micelles and biopolymer.

English abstract

Capability of phospholipids with positive charge to form complexes with hyaluronan in aqueous solutions, in a similar way as traditional cationic surfactants, was investigated by fluorescence probes. DPPC and lecithin aggregate in aqueous solution to form micelle-like structures capable to solubilize hydrophobic molecules. Changes in aggregation behavior after adding hyaluronan were observed only in the case of lecithin. Further, non-ionic biocompatible surfactant was used as additional dispersion environment in phospholipid-hyaluronan system with phospholipid molecules acting as a physical linker bonding micelles and biopolymer.

Keywords

fluorescence probe, hyaluronan, interactions, phospholipid

RIV year

2011

Released

01.10.2011

Publisher

Academic Press

Location

Burlington

ISBN

978-0-12-387720-8

Book

Advances in Planar Lipid Bilayers and Liposomes

Edition

není

Edition number

14

Pages from

235

Pages to

255

Pages count

21

BibTex


@inbook{BUT74322,
  author="Filip {Mravec} and Martina {Klučáková} and Miloslav {Pekař}",
  title="Fluorescence Spectroscopy Study of Hyaluronan-Phospholipid Interactions",
  annote="Capability of phospholipids with positive charge to form complexes with hyaluronan in aqueous solutions, in a similar way as traditional cationic surfactants, was investigated by fluorescence probes. DPPC and lecithin aggregate in aqueous solution to form micelle-like structures capable to solubilize hydrophobic molecules. Changes in aggregation behavior after adding hyaluronan were observed only in the case of lecithin. Further, non-ionic biocompatible surfactant was used as additional dispersion environment in phospholipid-hyaluronan system with phospholipid molecules acting as a physical linker bonding micelles and biopolymer.",
  address="Academic Press",
  booktitle="Advances in Planar Lipid Bilayers and Liposomes",
  chapter="74322",
  edition="není",
  howpublished="print",
  institution="Academic Press",
  year="2011",
  month="october",
  pages="235--255",
  publisher="Academic Press",
  type="book chapter"
}