Publication detail

Characterization and degradation behaviour of biocompatible triblock copolymer

MRAVCOVÁ, L. VOJTOVÁ, L. VÁVROVÁ, M. ČÁSLAVSKÝ, J. JANČÁŘ, J.

Original Title

Characterization and degradation behaviour of biocompatible triblock copolymer

English Title

Characterization and degradation behaviour of biocompatible triblock copolymer

Type

conference proceedings

Language

en

Original Abstract

Poly(lactic acid) and poly(glycolic acid) have been under extensive study since they were introduced as biodegradable polymers having hydrolytically unstable backbones. Therefore, these biopolymers can be used for a certain type of biomedical application such as injectable polymer drug delivery systems, tissue implants or resorbable bone adhesives. The prevailing mechanism for the biopolymer degradation is a simple random chemical hydrolysis. This work is focused on the studying of the thermoreversible behaviours of two copolymers, PLGA-PEG-PLGA and the same but modified with itaconic acid (ITA-PLGA-PEG-PLGA-ITA).

English abstract

Poly(lactic acid) and poly(glycolic acid) have been under extensive study since they were introduced as biodegradable polymers having hydrolytically unstable backbones. Therefore, these biopolymers can be used for a certain type of biomedical application such as injectable polymer drug delivery systems, tissue implants or resorbable bone adhesives. The prevailing mechanism for the biopolymer degradation is a simple random chemical hydrolysis. This work is focused on the studying of the thermoreversible behaviours of two copolymers, PLGA-PEG-PLGA and the same but modified with itaconic acid (ITA-PLGA-PEG-PLGA-ITA).

Keywords

biocompatible, copolymer, bone adhesives, sol-gel

Released

05.12.2006

Publisher

Faculty of Chemistry

Location

Brno, Czech Republic

ISBN

80-214-3320-5

Book

Book of abstracts

Edition

+1

Edition number

1

Pages from

212

Pages to

212

Pages count

1

URL

BibTex


@proceedings{BUT65899,
  author="Ludmila {Mravcová} and Lucy {Vojtová} and Milada {Vávrová} and Josef {Čáslavský} and Josef {Jančář}",
  title="Characterization and degradation behaviour of biocompatible triblock copolymer",
  annote="Poly(lactic acid) and poly(glycolic acid) have been under extensive study since they were introduced as biodegradable polymers having hydrolytically unstable backbones. Therefore, these biopolymers can be used for a certain type of biomedical application such as injectable polymer drug delivery systems, tissue implants or resorbable bone adhesives. The prevailing mechanism for the biopolymer degradation is a simple random chemical hydrolysis. This work is focused on the studying of the thermoreversible behaviours of two copolymers, PLGA-PEG-PLGA and the same but modified with itaconic acid (ITA-PLGA-PEG-PLGA-ITA).",
  address="Faculty of Chemistry",
  booktitle="Book of abstracts",
  chapter="65899",
  edition="+1",
  institution="Faculty of Chemistry",
  year="2006",
  month="december",
  pages="212--212",
  publisher="Faculty of Chemistry",
  type="conference proceedings"
}