Publication detail

Ex-vivo Evaluation of Newly Formed Bone After Lumbar Interbody Fusion Surgery Using X-ray Micro Computed Tomography

LÁZŇOVSKÝ, J. BŘÍNEK, A. ZIKMUND, T. KAISER, J.

Original Title

Ex-vivo Evaluation of Newly Formed Bone After Lumbar Interbody Fusion Surgery Using X-ray Micro Computed Tomography

Type

conference paper

Language

English

Original Abstract

Many novel biomaterials are recently investigated for use in spinal fusion surgery, especially in lumbar interbody fusion. The X-ray microCT as a tool is widely used for evaluating how successfully those biomaterials can perform a vertebral fusion. However, the current methodologies of microCT image assessment are based on visual evaluation by the operator. In this paper, we propose a methodology for how such biomaterials can be investigated in pre-clinical studies by investigating fused vertebrae morphology. We utilized microCT scans of pigs’ fused vertebrae to develop a fully automatic approach, which can characterize the morphometry of the bone in the fused region. A surface mesh model was created to extract the newly formed bone tissue between fused vertebrae in the microCT data. Extracted bone tissue was consequently evaluated according to the selected morphometric parameters. Characterization of the newly formed bone properties in the intervertebral area can be utilized to evaluate the osteogenesis function of implants used in lumbar interbody fusion surgery.

Keywords

X-ray micro computed tomography; Intervertebral fusion; Image processing; Lumbar interbody fusion; Quantitative tomography

Authors

LÁZŇOVSKÝ, J.; BŘÍNEK, A.; ZIKMUND, T.; KAISER, J.

Released

20. 12. 2023

Publisher

Springer Nature Singapore

Location

Singapore

ISBN

978-981-16-6774-9

Book

Medical Imaging and Computer-Aided Diagnosis

ISBN

1876-1100

Periodical

Lecture notes in Electrical Engineering

Year of study

810

State

United Kingdom of Great Britain and Northern Ireland

Pages from

101

Pages to

110

Pages count

10

URL

https://link.springer.com/chapter/10.1007/978-981-16-6775-6_9

BibTex

@inproceedings{BUT187030,
  author="Jakub {Lázňovský} and Adam {Břínek} and Tomáš {Zikmund} and Jozef {Kaiser}",
  title="Ex-vivo Evaluation of Newly Formed Bone After Lumbar Interbody Fusion Surgery Using X-ray Micro Computed Tomography",
  booktitle="Medical Imaging and Computer-Aided Diagnosis",
  year="2023",
  journal="Lecture notes in Electrical Engineering",
  volume="810",
  pages="101--110",
  publisher="Springer Nature Singapore",
  address="Singapore",
  doi="10.1007/978-981-16-6775-6\{_}9",
  isbn="978-981-16-6774-9",
  issn="1876-1100",
  url="https://link.springer.com/chapter/10.1007/978-981-16-6775-6_9"
}