Publication detail

Coherence controlled holographic microscopy – a tool for detection of new biomarkers of head and neck squamous cell carcinoma

VESELÝ, M. GÁL, B. ROTTENBERG, J. PALENIK, M. HANÁK, J. ZICHA, D.

Original Title

Coherence controlled holographic microscopy – a tool for detection of new biomarkers of head and neck squamous cell carcinoma

Type

journal article in Scopus

Language

English

Original Abstract

Background: Squamous cell carcinoma of the head and neck is characterized by local invasive-ness and metastases to regional lymph nodes. In 60% of cases, these tumours are diagnosed at an advanced stage, and the prognosis is unfavorable. One of the important factors of local, hematogenous or lymphogenic spread of the tumour in the human body is tumour cells‘ migration ability. Advanced microscopic methods provide a new perspective on cell migration. Purpose: This paper presents a coherence controlled holographic microscopy method that pro-vides a non-invasive quantitative evaluation of morphological and dynamic properties of living tumour cells. In connection with this method, new potential bio markers are emerging, the significance of which, however, needs to be verified by correlation with clinical data.

Keywords

cell migration; epithelial-mesenchymal transition; head and neck carcinoma, coherence-controlled holographic microscopy; squamous cell carcinoma; tumor markers

Authors

VESELÝ, M.; GÁL, B.; ROTTENBERG, J.; PALENIK, M.; HANÁK, J.; ZICHA, D.

Released

1. 2. 2022

ISBN

0862-495X

Periodical

Klinicka Onkologie

Year of study

35

Number

2

State

Czech Republic

Pages from

128

Pages to

131

Pages count

4

URL

BibTex

@article{BUT182706,
  author="Miroslav {Veselý} and Břetislav {Gál} and Jan {Rottenberg} and Michal {Palenik} and Jan {Hanák} and Daniel {Zicha}",
  title="Coherence controlled holographic microscopy – a tool for detection of new biomarkers of head and neck squamous cell carcinoma",
  journal="Klinicka Onkologie",
  year="2022",
  volume="35",
  number="2",
  pages="128--131",
  doi="10.48095/ccko2022128",
  issn="0862-495X",
  url="https://www.linkos.cz/casopis-klinicka-onkologie/2022-04-15-2/koherenci-rizena-holograficka-mikroskopie-nastroj-pro-hledani-novych-bio-markeru/"
}