Publication detail

Novel Hydrogel Material with Tailored Internal Architecture Modified by “Bio” Amphiphilic Components—Design and Analysis by a Physico-Chemical Approach

HEGER, R. KADLEC, M. TRUDIČOVÁ, M. ZINKOVSKA, N. HAJZLER, J. PEKAŘ, M. SMILEK, J.

Original Title

Novel Hydrogel Material with Tailored Internal Architecture Modified by “Bio” Amphiphilic Components—Design and Analysis by a Physico-Chemical Approach

Type

journal article in Web of Science

Language

English

Original Abstract

Nowadays, hydrogels are found in many applications ranging from the industrial to the biological (e.g., tissue engineering, drug delivery systems, cosmetics, water treatment, and many more). According to the specific needs of individual applications, it is necessary to be able to modify the properties of hydrogel materials, particularly the transport and mechanical properties related to their structure, which are crucial for the potential use of the hydrogels in modern material engineering. Therefore, the possibility of preparing hydrogel materials with tunable properties is a very real topic and is still being researched. A simple way to modify these properties is to alter the internal structure by adding another component. The addition of natural substances is convenient due to their biocompatibility and the possibility of biodegradation. Therefore, this work focused on hydrogels modified by a substance that is naturally found in the tissues of our body, namely lecithin. Hydrogels were prepared by different types of crosslinking (physical, ionic, and chemical). Their mechanical properties were monitored and these investigations were supplemented by drying and rehydration measurements, and supported by the morphological characterization of xerogels. With the addition of natural lecithin, it is possible to modify crucial properties of hydrogels such as porosity and mechanical properties, which will play a role in the final applications.

Keywords

lecithin; hydrogel; rheology; scanning electron microscopy; drying and swelling; extracellular matrix; mesh size

Authors

HEGER, R.; KADLEC, M.; TRUDIČOVÁ, M.; ZINKOVSKA, N.; HAJZLER, J.; PEKAŘ, M.; SMILEK, J.

Released

13. 2. 2022

Publisher

MDPI

Location

Basel, Switzerland

ISBN

2310-2861

Periodical

Gels

Year of study

8

Number

2

State

Swiss Confederation

Pages from

1

Pages to

23

Pages count

23

URL

https://www.mdpi.com/2310-2861/8/2/115

Full text in the Digital Library

http://hdl.handle.net/11012/203935

BibTex

@article{BUT176575,
  author="Richard {Heger} and Martin {Kadlec} and Monika {Trudičová} and Natalia {Zinkovska} and Jan {Hajzler} and Miloslav {Pekař} and Jiří {Smilek}",
  title="Novel Hydrogel Material with Tailored Internal Architecture Modified by “Bio” Amphiphilic Components—Design and Analysis by a Physico-Chemical Approach",
  journal="Gels",
  year="2022",
  volume="8",
  number="2",
  pages="1--23",
  doi="10.3390/gels8020115",
  issn="2310-2861",
  url="https://www.mdpi.com/2310-2861/8/2/115"
}