Publication detail

Multiscale experimental evaluation of agarose-based semi-interpenetrating polymer network hydrogels as materials with tunable rheological and transport performance

TRUDIČOVÁ, M. SMILEK, J. KALINA, M. SMILKOVÁ, M. ADÁMKOVÁ, K. HRUBANOVÁ, K. KRZYŽÁNEK, V. SEDLÁČEK, P.

Original Title

Multiscale experimental evaluation of agarose-based semi-interpenetrating polymer network hydrogels as materials with tunable rheological and transport performance

Type

journal article in Web of Science

Language

English

Original Abstract

This study introduces an original concept in the development of hydrogel materials for controlled release of charged organic compounds based on semi-interpenetrating polymer networks composed by an inert gel-forming polymer component and interpenetrating linear polyelectrolyte with specific binding affinity towards the carried active compound. As it is experimentally illustrated on the prototype hydrogels prepared from agarose interpenetrated by poly(styrene sulfonate) (PSS) and alginate (ALG), respectively, the main benefit brought by this concept is represented by the ability to tune the mechanical and transport performance of the material independently via manipulating the relative content of the two structural components. A unique analytical methodology is proposed to provide complex insight into composition–structure– performance relationships in the hydrogel material combining methods of analysis on the macroscopic scale, but also in the specific microcosms of the gel network. Rheological analysis has confirmed that the complex modulus of the gels can be adjusted in a wide range by the gelling component (agarose) with negligible effect of the interpenetrating component (PSS or ALG). On the other hand, the content of PSS as low as 0.01 wt.% of the gel resulted in a more than 10-fold decrease of diffusivity of model-charged organic solute (Rhodamine 6G).

Keywords

hydrogels; semi-interpenetrating polymer networks; controlled release systems; rheology; diffusion; cryo-scanning electron microscopy

Authors

TRUDIČOVÁ, M.; SMILEK, J.; KALINA, M.; SMILKOVÁ, M.; ADÁMKOVÁ, K.; HRUBANOVÁ, K.; KRZYŽÁNEK, V.; SEDLÁČEK, P.

Released

31. 10. 2020

Publisher

MDPI

Location

Basel, Switzerland

ISBN

2073-4360

Periodical

Polymers

Year of study

12

Number

11

State

Swiss Confederation

Pages from

1

Pages to

25

Pages count

25

URL

https://www.mdpi.com/2073-4360/12/11/2561

Full text in the Digital Library

http://hdl.handle.net/11012/195667

BibTex

@article{BUT166087,
  author="Monika {Trudičová} and Jiří {Smilek} and Michal {Kalina} and Marcela {Smilková} and Kateřina {Adámková} and Kamila {Hrubanová} and Vladislav {Krzyžánek} and Petr {Sedláček}",
  title="Multiscale experimental evaluation of agarose-based semi-interpenetrating polymer network hydrogels as materials with tunable rheological and transport performance",
  journal="Polymers",
  year="2020",
  volume="12",
  number="11",
  pages="1--25",
  doi="10.3390/polym12112561",
  issn="2073-4360",
  url="https://www.mdpi.com/2073-4360/12/11/2561"
}

Documents

polymers-12-02561-v2.pdf