Publication detail

Influence of pH and Its Changes on the System of Phase-Separated Hydrogels

HEGER, R. MRAVEC, F.

Original Title

Influence of pH and Its Changes on the System of Phase-Separated Hydrogels

Type

abstract

Language

English

Original Abstract

The main focus of this work is to monitor how pH and its changes affect the properties of phase-separated hydrogels. Hydrogels were prepared by the interaction of polyelectrolyte and oppositely charged surfactant. In this work it was interaction of hyaluronan and Septonex. The studied pH range was 4-9. Changes in pH were simply observed and controlled by spectroscopic indicators. The main method for describing changes in the properties before and after pH change was rheology. The rheology was measured for all prepared hydrogels as well as for hydrogels that had changed pH. The pH values were always changed to the limit values of the selected range, i.e. four and nine. It has been shown that by changing the pH, the mechanical properties and partly also the internal structure of the hydrogel can be adjusted. The rheological results show that the hydrogels prepared at pH 9 and 7 seem to be the most interesting for their possible application use. Hydrogels prepared at pH 9 have the strongest bonds, but low permeability, and hydrogels prepared at pH 7, which in turn are very soft and are able to absorb large amounts of water. By changing the pH of the dispersion medium, it was possible to strengthen the formed bonds during the change to pH 9 and vice versa by changing to pH 4 the bonds were softened.

Keywords

hydrogel, pH, rheology, hyaluronan, Septonex

Authors

HEGER, R.; MRAVEC, F.

Released

21. 11. 2019

Publisher

Vysoké učení technické v Brně, Fakulta chemická

Location

Brno

ISBN

978-80-214-5807-9

Book

Studentská odborná konference Chemie je život - Sborník abstraktů

Edition number

1

Pages from

48

Pages to

48

Pages count

1

BibTex

@misc{BUT161827,
  author="Richard {Heger} and Filip {Mravec}",
  title="Influence of pH and Its Changes on the System of Phase-Separated Hydrogels",
  booktitle="Studentská odborná konference Chemie je život - Sborník abstraktů",
  year="2019",
  edition="1",
  pages="48--48",
  publisher="Vysoké učení technické v Brně, Fakulta chemická",
  address="Brno",
  isbn="978-80-214-5807-9",
  note="abstract"
}