Publication detail

Cytotoxicity of Shear Exfoliated Pnictogen (As, Sb, Bi) Nanosheets

CHIA, H. LATIFF, N. GUSMÃO, R. SOFER, Z. PUMERA, M.

Original Title

Cytotoxicity of Shear Exfoliated Pnictogen (As, Sb, Bi) Nanosheets

Type

journal article in Web of Science

Language

English

Original Abstract

The experimental achievement of phosphorene, which exhibits superior electronic, physical, and optical properties has spurred recent interest in other Group 15 elemental 2D nanomaterials such as arsenene, antimonene, and bismuthene. These unique and superior properties of the pnictogen nanosheets have spurred intensive research efforts and led to the discovery of their diversified potential applications; for instance, optical Kerr material, photonic devices, pnictogen-decorated microfibers, high-speed transistors, and flexible 2D electronics. Previous studies have mainly been dedicated to study the synthesis, properties, and applications of the heavy pnictogens nanosheets; however, the toxicological behaviour of these nanosheets has yet to be established. Herein, the cytotoxicity study of pnictogen nanosheets (As, Sb, and B) was conducted over 24 h of incubation with various concentrations of test materials and adenocarcinoma human lung epithelial A549 cells. After the treatment period, the remaining cell viabilities were obtained through absorbance measurements with WST-8 and MTT assays. These findings demonstrate that the toxicity of pnictogen nanosheets decreases down Group 15, whereby arsenic nanosheets are considered to be the most toxic, whereas bismuth nanosheets induce low cytotoxicity. The findings of this study constitute an important initial step towards enhancing our understanding of the toxicological effects of pnictogen nanosheets in light of their prospective commercial applications.

Keywords

cell viability; cytotoxicity; layered materials; phosphorene; pnictogen nanosheets

Authors

CHIA, H.; LATIFF, N.; GUSMÃO, R.; SOFER, Z.; PUMERA, M.

Released

11. 2. 2019

ISBN

0947-6539

Periodical

CHEMISTRY-A EUROPEAN JOURNAL

Year of study

25

Number

9

State

Federal Republic of Germany

Pages from

2242

Pages to

2249

Pages count

8

URL

https://onlinelibrary.wiley.com/doi/full/10.1002/chem.201804336

BibTex

@article{BUT158444,
  author="Hui Ling {Chia} and Naziah Mohamad {Latiff} and Rui {Gusmão} and Zdeněk {Sofer} and Martin {Pumera}",
  title="Cytotoxicity of Shear Exfoliated Pnictogen (As, Sb, Bi) Nanosheets",
  journal="CHEMISTRY-A EUROPEAN JOURNAL",
  year="2019",
  volume="25",
  number="9",
  pages="2242--2249",
  doi="10.1002/chem.201804336",
  issn="0947-6539",
  url="https://onlinelibrary.wiley.com/doi/full/10.1002/chem.201804336"
}