Publication detail

DEAE/SDS and chitosan/SDS hydrogels

JARÁBKOVÁ, S. SMILEK, J. MRAVEC, F. PEKAŘ, M.

Original Title

DEAE/SDS and chitosan/SDS hydrogels

English Title

DEAE/SDS and chitosan/SDS hydrogels

Type

conference paper

Language

en

Original Abstract

This work is focused on ionic interactions between oppositely charged polyelectrolytes and surfactants which can – under proper conditions – lead to formation of physical gels. Surfactants form micellar structures enabling to solubilize hydrophobic substances in the otherwise aqueous environment of the gel. Resulting materials can find use in the formulation of delivery systems, e.g. hydrophobic drugs especially in topical applications. Main aim of this work is to study rheological properties and preparation techniques of materials, that are formed from positively charged polysaccharides (chitosan, cationized dextrane) and negatively charged surfactant (SDS). The presence of hydrophobic nanodomains was tested by solubilization of hydrophobic dyes (e.g. Oil red O, prodan).

English abstract

This work is focused on ionic interactions between oppositely charged polyelectrolytes and surfactants which can – under proper conditions – lead to formation of physical gels. Surfactants form micellar structures enabling to solubilize hydrophobic substances in the otherwise aqueous environment of the gel. Resulting materials can find use in the formulation of delivery systems, e.g. hydrophobic drugs especially in topical applications. Main aim of this work is to study rheological properties and preparation techniques of materials, that are formed from positively charged polysaccharides (chitosan, cationized dextrane) and negatively charged surfactant (SDS). The presence of hydrophobic nanodomains was tested by solubilization of hydrophobic dyes (e.g. Oil red O, prodan).

Keywords

hydrogels, cationized dextran, chitosan, rheology, solubilization, nanodomains, negatively charged surfactant

Released

30.05.2017

Publisher

Masaryk University

Location

Brno

ISBN

978-80-210-8580-0

Book

XVII. Workshop of Physical Chemists and Electrochemists Book of abstracts

Edition

1

Pages from

62

Pages to

63

Pages count

2

BibTex


@inproceedings{BUT138772,
  author="Sabína {Jarábková} and Jiří {Smilek} and Filip {Mravec} and Miloslav {Pekař}",
  title="DEAE/SDS and chitosan/SDS hydrogels",
  annote="This work is focused on ionic interactions between oppositely charged polyelectrolytes and surfactants which can – under proper conditions – lead to formation of physical gels. Surfactants form micellar structures enabling to solubilize hydrophobic substances in the otherwise aqueous environment of the gel. Resulting materials can find use in the formulation of delivery systems, e.g. hydrophobic drugs especially in topical applications. Main aim of this work is to study rheological properties and preparation techniques of materials, that are formed from positively charged polysaccharides (chitosan, cationized dextrane) and negatively charged surfactant (SDS). The presence of hydrophobic nanodomains was tested by solubilization of hydrophobic dyes (e.g. Oil red O, prodan).",
  address="Masaryk University",
  booktitle="XVII. Workshop of Physical Chemists and Electrochemists
Book of abstracts",
  chapter="138772",
  edition="1",
  howpublished="electronic, physical medium",
  institution="Masaryk University",
  year="2017",
  month="may",
  pages="62--63",
  publisher="Masaryk University",
  type="conference paper"
}