Publication detail

Electrospun biodegradable PCL, PEG and PCL/PEG polyurethane nanofibers coated by amine rich plasma polymers

KEDROŇOVÁ, E., KUPKA, V., MANAKHOV, A., STOICA, A., VOJTOVÁ, L., ZAJÍČKOVÁ, L.

Original Title

Electrospun biodegradable PCL, PEG and PCL/PEG polyurethane nanofibers coated by amine rich plasma polymers

English Title

Electrospun biodegradable PCL, PEG and PCL/PEG polyurethane nanofibers coated by amine rich plasma polymers

Type

conference paper

Language

en

Original Abstract

The electrospinning process was employed for the preparation of nanofiber substrates based on hydrophobic poly(caprolactone) (PCL), hydrophilic poly(ethylene glycol) (PEG) and amphiphilic PCL/PEG linear polyurethane (PUR). Thin amine layer by means of the cyclopropylamine plasma polymerization in radio frequency capacitively coupled discharge was deposited on prepared nanofibrous meshes. The possibility for further functionalizing by grafting with chitosan biopolymer through carbodiimide-mediated coupling via citric acid has been tested on a model PCL/PEG PUR foil. Infrared spectroscopy confirmed successful grafting of chitosan onto the PUR surface. Optimizing PUR nanofibers processing can open possible use of the material in wound healing applications exploiting antibacterial properties of chitosan and excellent elasticity, controlled biodegradability and optimal stiffness of PUR.

English abstract

The electrospinning process was employed for the preparation of nanofiber substrates based on hydrophobic poly(caprolactone) (PCL), hydrophilic poly(ethylene glycol) (PEG) and amphiphilic PCL/PEG linear polyurethane (PUR). Thin amine layer by means of the cyclopropylamine plasma polymerization in radio frequency capacitively coupled discharge was deposited on prepared nanofibrous meshes. The possibility for further functionalizing by grafting with chitosan biopolymer through carbodiimide-mediated coupling via citric acid has been tested on a model PCL/PEG PUR foil. Infrared spectroscopy confirmed successful grafting of chitosan onto the PUR surface. Optimizing PUR nanofibers processing can open possible use of the material in wound healing applications exploiting antibacterial properties of chitosan and excellent elasticity, controlled biodegradability and optimal stiffness of PUR.

Keywords

Electrospinning, Polymer nanofibers, Biodegradable polyurethanes, Plasma Amine Coatings

Released

19.10.2016

Publisher

Tanger Ltd.

Location

Ostrava, Nanocon 2016 - Proceedings

ISBN

978-80-87294-71-0

Book

NANOCON 2016 - Conference Proceedings

Edition

1

Pages from

490

Pages to

496

Pages count

7

URL

BibTex


@inproceedings{BUT136071,
  author="Vojtěch {Kupka} and Lucy {Vojtová}",
  title="Electrospun biodegradable PCL, PEG and PCL/PEG polyurethane nanofibers coated by amine rich plasma polymers",
  annote="The electrospinning process was employed for the preparation of nanofiber substrates based on hydrophobic poly(caprolactone) (PCL), hydrophilic poly(ethylene glycol) (PEG) and amphiphilic PCL/PEG linear polyurethane (PUR). Thin amine layer by means of the cyclopropylamine plasma polymerization in radio frequency capacitively coupled discharge was deposited on prepared nanofibrous meshes. The possibility for further functionalizing by grafting with chitosan biopolymer through carbodiimide-mediated coupling via citric acid has been tested on a model PCL/PEG PUR foil. Infrared spectroscopy confirmed successful grafting of chitosan onto the PUR surface. Optimizing PUR nanofibers processing can open possible use of the material in wound healing applications exploiting antibacterial properties of chitosan and excellent elasticity, controlled biodegradability and optimal stiffness of PUR.",
  address="Tanger Ltd.",
  booktitle="NANOCON 2016 - Conference Proceedings",
  chapter="136071",
  edition="1",
  howpublished="print",
  institution="Tanger Ltd.",
  year="2016",
  month="october",
  pages="490--496",
  publisher="Tanger Ltd.",
  type="conference paper"
}