Publication detail

Correlation between transversal and orthogonal maximal diameters of abdominal aortic aneurysms and alternative rupture risk predictors

NOVÁK, K. POLZER, S. KŘIVKA, T. VLACHOVSKÝ, R. STAFFA, R. KUBÍČEK, L. LAMBERT, L. BURŠA, J.

Original Title

Correlation between transversal and orthogonal maximal diameters of abdominal aortic aneurysms and alternative rupture risk predictors

English Title

Correlation between transversal and orthogonal maximal diameters of abdominal aortic aneurysms and alternative rupture risk predictors

Type

journal article in Web of Science

Language

en

Original Abstract

Purpose: There is no standard for measuring maximal diameter (Dmax) of abdominal aortic aneurysm (AAA) from computer tomography (CT) images although differences between Dmax evaluated from transversal (axialDmax) or orthogonal (orthoDmax) planes can be large especially for angulated AAAs. Therefore we investigated their correlations with alternative rupture risk indicators as peak wall stress (PWS) and peak wall rupture risk (PWRR) to decide which Dmax is more relevant in AAA rupture risk assessment. Material and Methods The Dmax values were measured by a trained radiologist from 70 collected CT scans, and the corresponding PWS and PWRR were evaluated using Finite Element Analysis (FEA). The cohort was ordered according to the difference between axialDmax and orthoDmax ( Da-o) quantifying the aneurysm angulation, and Spearman’s correlation coefficients between PWS/PWRR – orthoDmax/axialDmax were calculated. Results The calculated correlations PWS/PWRR vs. orthoDmax were substantially higher for angulated AAAs (with Da-o >= 3mm ). Under this limit, the correlations were almost the same for both Dmax values. Analysis of AAAs divided into two groups of angulated (n=38) and straight (n=32) cases revealed that both groups are similar in all parameters (orthoDmax, PWS, PWRR) with the exception of axialDmax (p=0.024). Conclusions It was confirmed that orthoDmax is better correlated with the alternative rupture risk predictors PWS and PWRR for angulated AAAs ( Da-o>=3mm) while there is no difference between orthoDmax and axialDmax for straight AAAs ( Da-o<3). As angulated AAAs represent a significant portion of cases it can be recommended to use orthoDmax as the only Dmax parameter for AAA rupture risk assessment.

English abstract

Purpose: There is no standard for measuring maximal diameter (Dmax) of abdominal aortic aneurysm (AAA) from computer tomography (CT) images although differences between Dmax evaluated from transversal (axialDmax) or orthogonal (orthoDmax) planes can be large especially for angulated AAAs. Therefore we investigated their correlations with alternative rupture risk indicators as peak wall stress (PWS) and peak wall rupture risk (PWRR) to decide which Dmax is more relevant in AAA rupture risk assessment. Material and Methods The Dmax values were measured by a trained radiologist from 70 collected CT scans, and the corresponding PWS and PWRR were evaluated using Finite Element Analysis (FEA). The cohort was ordered according to the difference between axialDmax and orthoDmax ( Da-o) quantifying the aneurysm angulation, and Spearman’s correlation coefficients between PWS/PWRR – orthoDmax/axialDmax were calculated. Results The calculated correlations PWS/PWRR vs. orthoDmax were substantially higher for angulated AAAs (with Da-o >= 3mm ). Under this limit, the correlations were almost the same for both Dmax values. Analysis of AAAs divided into two groups of angulated (n=38) and straight (n=32) cases revealed that both groups are similar in all parameters (orthoDmax, PWS, PWRR) with the exception of axialDmax (p=0.024). Conclusions It was confirmed that orthoDmax is better correlated with the alternative rupture risk predictors PWS and PWRR for angulated AAAs ( Da-o>=3mm) while there is no difference between orthoDmax and axialDmax for straight AAAs ( Da-o<3). As angulated AAAs represent a significant portion of cases it can be recommended to use orthoDmax as the only Dmax parameter for AAA rupture risk assessment.

Keywords

Abdominal aortic aneurysm; Correlation analysis, Maximal diameter, Peak wall stress, Peak wall rupture risk

Released

01.04.2017

Publisher

Elsevier

Location

Amsterdam, Nizozemsko

Pages from

151

Pages to

156

Pages count

6

URL

Documents

BibTex


@article{BUT134010,
  author="Kamil {Novák} and Stanislav {Polzer} and Tomáš {Křivka} and Robert {Vlachovský} and Robert {Staffa} and Luboš {Kubíček} and Lukáš {Lambert} and Jiří {Burša}",
  title="Correlation between transversal and orthogonal maximal diameters of abdominal aortic aneurysms and alternative rupture risk predictors",
  annote="Purpose: 
There is no standard for measuring maximal diameter (Dmax) of abdominal aortic
aneurysm (AAA) from computer tomography (CT) images although differences between
Dmax evaluated from transversal (axialDmax) or orthogonal (orthoDmax) planes can be large
especially for angulated AAAs. Therefore we investigated their correlations with alternative
rupture risk indicators as peak wall stress (PWS) and peak wall rupture risk (PWRR) to decide
which Dmax is more relevant in AAA rupture risk assessment.

Material and Methods
The Dmax values were measured by a trained radiologist from 70 collected CT scans, and the
corresponding PWS and PWRR were evaluated using Finite Element Analysis (FEA). The
cohort was ordered according to the difference between axialDmax and orthoDmax ( Da-o)
quantifying the aneurysm angulation, and Spearman’s correlation coefficients between
PWS/PWRR – orthoDmax/axialDmax were calculated.

Results
The calculated correlations PWS/PWRR vs. orthoDmax were substantially higher for
angulated AAAs (with Da-o >= 3mm ). Under this limit, the correlations were almost the same
for both Dmax values. Analysis of AAAs divided into two groups of angulated (n=38) and
straight (n=32) cases revealed that both groups are similar in all parameters (orthoDmax,
PWS, PWRR) with the exception of axialDmax (p=0.024).

Conclusions
It was confirmed that orthoDmax is better correlated with the alternative rupture risk
predictors PWS and PWRR for angulated AAAs ( Da-o>=3mm) while there is no difference
between orthoDmax and axialDmax for straight AAAs ( Da-o<3). As angulated AAAs
represent a significant portion of cases it can be recommended to use orthoDmax as the only
Dmax parameter for AAA rupture risk assessment.",
  address="Elsevier",
  chapter="134010",
  doi="10.1016/j.compbiomed.2017.03.005",
  howpublished="online",
  institution="Elsevier",
  number="3",
  volume="83",
  year="2017",
  month="april",
  pages="151--156",
  publisher="Elsevier",
  type="journal article in Web of Science"
}