Publication detail

Prediction of localized aerosol deposition in a realistic replica of human airways using experimental data and numerical simulation

LÍZAL, F. ELCNER, J. BĚLKA, M. JEDELSKÝ, J. JÍCHA, M.

Original Title

Prediction of localized aerosol deposition in a realistic replica of human airways using experimental data and numerical simulation

English Title

Prediction of localized aerosol deposition in a realistic replica of human airways using experimental data and numerical simulation

Type

conference paper

Language

en

Original Abstract

The presence of aerosol deposition hot-spots in human airways presumably contributes to development of various diseases. The overall aerosol deposition in human lungs can be predicted with sufficient accuracy nowadays. However, the prediction of localized aerosol deposition poses arduous challenge, namely in diseased lungs. Numerical simulation is considered to be a promising tool for the successful prediction. Yet, the validation of such simulations is difficult to perform, as not enough experimental data acquired using realistic airway replicas is available. This paper presents a first comparison of localized deposition measurement and simulation performed on the identical realistic geometry. The analysis indicates that both approaches yield similar results for low Reynolds number flows.

English abstract

The presence of aerosol deposition hot-spots in human airways presumably contributes to development of various diseases. The overall aerosol deposition in human lungs can be predicted with sufficient accuracy nowadays. However, the prediction of localized aerosol deposition poses arduous challenge, namely in diseased lungs. Numerical simulation is considered to be a promising tool for the successful prediction. Yet, the validation of such simulations is difficult to perform, as not enough experimental data acquired using realistic airway replicas is available. This paper presents a first comparison of localized deposition measurement and simulation performed on the identical realistic geometry. The analysis indicates that both approaches yield similar results for low Reynolds number flows.

Keywords

aerosol deposition, human lungs, human airways, computational fluid mechanics, experiment

Released

15.11.2016

Publisher

EDP Sciences

Pages from

1

Pages to

4

Pages count

4

URL

Full text in the Digital Library

BibTex


@inproceedings{BUT131497,
  author="František {Lízal} and Jakub {Elcner} and Miloslav {Bělka} and Jan {Jedelský} and Miroslav {Jícha}",
  title="Prediction of localized aerosol deposition in a realistic replica of human airways using experimental data and numerical simulation",
  annote="The presence of aerosol deposition hot-spots in human airways presumably contributes to development of various diseases. The overall aerosol deposition in human lungs can be predicted with sufficient accuracy nowadays. However, the prediction of localized aerosol deposition poses arduous challenge, namely in diseased lungs. Numerical simulation is considered to be a promising tool for the successful prediction. Yet, the validation of such simulations is difficult to perform, as not enough experimental data acquired using realistic airway replicas is available. This paper presents a first comparison of localized deposition measurement and simulation performed on the identical realistic geometry. The analysis indicates that both approaches yield similar results for low Reynolds number flows.",
  address="EDP Sciences",
  booktitle="EPJ Web of Conferences",
  chapter="131497",
  doi="10.1051/epjconf/201714302067",
  howpublished="online",
  institution="EDP Sciences",
  year="2016",
  month="november",
  pages="1--4",
  publisher="EDP Sciences",
  type="conference paper"
}