Publication detail

Biodegradable poly (e-caprolactone)/gelatin nanofibers: Effect of tubular halloysite on structure and properties

ŠVACHOVÁ, V. VOJTOVÁ, L. PAVLIŇÁK, D. KHUNOVÁ, V.

Original Title

Biodegradable poly (e-caprolactone)/gelatin nanofibers: Effect of tubular halloysite on structure and properties

English Title

Biodegradable poly (e-caprolactone)/gelatin nanofibers: Effect of tubular halloysite on structure and properties

Type

conference paper

Language

en

Original Abstract

The work explores preparation of new advanced nanofibers based on biodegradable polymers and biocompatible tubular halloysite (HNT). Electrospun nanofibers comprising 8 wt% gelatin (Gel) and 8 wt% polycaprolactone (PCL) have been prepared by using eco-friendly solvent – acetic acid. The content of HNT in PCL/Gel nanofibers was 0.5, 1.0, 3.0, 6.0 and 9.0 wt%. It was found that the addition of HNT significantly affected the polymer mixture spinnability and the fiber diameter. SEM observations revealed that the structure of nanofibers depends on nanofiber composition. Whilst in nanofibers with lower HNT content uniform morphology with HNTs located merely inside the individual nanofibers has been observed, in nanofibers with 6 and 9 wt% HNT individual particles as well as the agglomerates of HNT have been detected in both, the inner part as well as outside part of nanofiber. Important reinforcing effect has been achieved in whole HNT content. The highest improvement has been reached when the HNT content was 0.5 wt%. In this case, multiple enhancements of strength (2x), elongation (4x) and modulus (2x) have been confirmed. ATR-FTIR revealed that improvement of mechanical properties is also due to the increase of interface interaction in between PCL/Gel and HNT. The prepared PCL/Gel/HNT nanofibers can be used for tissue engineering and/or as drug carriers or signal molecules in whole spectrum of medical applications.

English abstract

The work explores preparation of new advanced nanofibers based on biodegradable polymers and biocompatible tubular halloysite (HNT). Electrospun nanofibers comprising 8 wt% gelatin (Gel) and 8 wt% polycaprolactone (PCL) have been prepared by using eco-friendly solvent – acetic acid. The content of HNT in PCL/Gel nanofibers was 0.5, 1.0, 3.0, 6.0 and 9.0 wt%. It was found that the addition of HNT significantly affected the polymer mixture spinnability and the fiber diameter. SEM observations revealed that the structure of nanofibers depends on nanofiber composition. Whilst in nanofibers with lower HNT content uniform morphology with HNTs located merely inside the individual nanofibers has been observed, in nanofibers with 6 and 9 wt% HNT individual particles as well as the agglomerates of HNT have been detected in both, the inner part as well as outside part of nanofiber. Important reinforcing effect has been achieved in whole HNT content. The highest improvement has been reached when the HNT content was 0.5 wt%. In this case, multiple enhancements of strength (2x), elongation (4x) and modulus (2x) have been confirmed. ATR-FTIR revealed that improvement of mechanical properties is also due to the increase of interface interaction in between PCL/Gel and HNT. The prepared PCL/Gel/HNT nanofibers can be used for tissue engineering and/or as drug carriers or signal molecules in whole spectrum of medical applications.

Keywords

nanofibers; electrospinning; halloysite nanotubes; polycaprolactone; gelatin

Released

19.06.2016

Publisher

AIP Conference Proceedings

Location

Italy

ISBN

9780735413900

Book

VIII International Conference on “Times of Polymers and Composites”

Edition

1736

Pages from

020059

Pages to

020063

Pages count

4

URL

Documents

BibTex


@inproceedings{BUT126756,
  author="Veronika {Pavliňáková} and Lucy {Vojtová} and David {Pavliňák} and Viera {Khunová}",
  title="Biodegradable poly (e-caprolactone)/gelatin nanofibers: Effect of tubular halloysite on structure and properties",
  annote="The work explores preparation of new advanced nanofibers based on biodegradable polymers and biocompatible tubular halloysite (HNT). Electrospun nanofibers comprising 8 wt% gelatin (Gel) and 8 wt% polycaprolactone (PCL) have been prepared by using eco-friendly solvent – acetic acid. The content of HNT in PCL/Gel nanofibers was 0.5, 1.0, 3.0, 6.0 and 9.0 wt%. It was found that the addition of HNT significantly affected the polymer mixture spinnability and the fiber diameter. SEM observations revealed that the structure of nanofibers depends on nanofiber composition. Whilst in nanofibers with lower HNT content uniform morphology with HNTs located merely inside the individual nanofibers has been observed, in nanofibers with 6 and 9 wt% HNT individual particles as well as the agglomerates of HNT have been detected in both, the inner part as well as outside part of nanofiber. Important reinforcing effect has been achieved in whole HNT content. The highest improvement has been reached when the HNT content was 0.5 wt%. In this case, multiple enhancements of strength (2x), elongation (4x) and modulus (2x) have been confirmed. ATR-FTIR revealed that improvement of mechanical properties is also due to the increase of interface interaction in between PCL/Gel and HNT. The prepared PCL/Gel/HNT nanofibers can be used for tissue engineering and/or as drug carriers or signal molecules in whole spectrum of medical applications.",
  address="AIP Conference Proceedings",
  booktitle="VIII International Conference on “Times of Polymers and Composites”",
  chapter="126756",
  doi="10.1063/1.4949634",
  edition="1736",
  howpublished="online",
  institution="AIP Conference Proceedings",
  number="1736",
  year="2016",
  month="june",
  pages="020059--020063",
  publisher="AIP Conference Proceedings",
  type="conference paper"
}