Publication detail

The utilization of freeze-drying method for solubilization of hydrophobes in the hydrophilic biopolymer environment

MICHALICOVÁ, P. MRAVEC, F. PEKAŘ, M.

Original Title

The utilization of freeze-drying method for solubilization of hydrophobes in the hydrophilic biopolymer environment

English Title

The utilization of freeze-drying method for solubilization of hydrophobes in the hydrophilic biopolymer environment

Type

abstract

Language

en

Original Abstract

Hyaluronan is a chemical with prevalent hydrophilic character in native form. This is the main limiting factor for the formation of the interactions with hydrophobic species without additional support. The main aim of this work was to utilize freeze-drying method to support desired interactions. Hydrophobic polarity-sensitive fluorescence probes were used as hydrophobic models or indicators of interactions with hydrophobic patches. By monitoring of their specific fluorescence parameters the presence of desired interactions was judged. The fluorescence parameters were studied by steady state fluorescence spectrometry.

English abstract

Hyaluronan is a chemical with prevalent hydrophilic character in native form. This is the main limiting factor for the formation of the interactions with hydrophobic species without additional support. The main aim of this work was to utilize freeze-drying method to support desired interactions. Hydrophobic polarity-sensitive fluorescence probes were used as hydrophobic models or indicators of interactions with hydrophobic patches. By monitoring of their specific fluorescence parameters the presence of desired interactions was judged. The fluorescence parameters were studied by steady state fluorescence spectrometry.

Keywords

native hyaluronan, freeze-drying, fluorescence spectroscopy, polarity

Released

03.12.2015

Publisher

Vysoké učení technické v Brně, Fakulta chemická

Location

Brno

ISBN

978-80-214-5290-9

Book

Sborník abstraků 3. prosince 2015, Studentská konference Chemie je život

Edition

1

Pages from

68

Pages to

68

Pages count

1

BibTex


@misc{BUT121570,
  author="Petra {Michalicová} and Filip {Mravec} and Miloslav {Pekař}",
  title="The utilization of freeze-drying method for solubilization of hydrophobes in the hydrophilic biopolymer environment",
  annote="Hyaluronan is a chemical with prevalent hydrophilic character in native form. This is the main limiting factor for the formation of the interactions with hydrophobic species without additional support. The main aim of this work was to utilize freeze-drying method to support desired interactions. Hydrophobic polarity-sensitive fluorescence probes were used as hydrophobic models or indicators of interactions with hydrophobic patches. By monitoring of their specific fluorescence parameters the presence of desired interactions was judged. The fluorescence parameters were studied by steady state fluorescence spectrometry.",
  address="Vysoké učení technické v Brně, Fakulta chemická",
  booktitle="Sborník abstraků 3. prosince 2015, Studentská konference Chemie je život",
  chapter="121570",
  edition="1",
  howpublished="print",
  institution="Vysoké učení technické v Brně, Fakulta chemická",
  year="2015",
  month="december",
  pages="68--68",
  publisher="Vysoké učení technické v Brně, Fakulta chemická",
  type="abstract"
}