Publication detail

Hyaluronic acid as a modulator of the cytotoxic effects of cationic surfactants

SAUEROVÁ, P. VERDÁNOVÁ, M. PILGROVÁ, T. VENEROVÁ, T. MRAVEC, F. KALBÁČOVÁ, M. PEKAŘ, M.

Original Title

Hyaluronic acid as a modulator of the cytotoxic effects of cationic surfactants

English Title

Hyaluronic acid as a modulator of the cytotoxic effects of cationic surfactants

Type

journal article in Web of Science

Language

en

Original Abstract

This work reported results of the study of colloidal complexes of CTAB or Septonex with oppositely charged hyaluronic acid (HyA), based primarily on electrostatic interactions, which were prepared with the aim to test potential modulation of surfactants cytotoxic effects. Data show that CTAB–HyA or Septonex–HyA complexes reduce (in different rate according to the used surfactant and HyA concentrations) cytotoxicity of both surfactants in all tested concentrations.

English abstract

This work reported results of the study of colloidal complexes of CTAB or Septonex with oppositely charged hyaluronic acid (HyA), based primarily on electrostatic interactions, which were prepared with the aim to test potential modulation of surfactants cytotoxic effects. Data show that CTAB–HyA or Septonex–HyA complexes reduce (in different rate according to the used surfactant and HyA concentrations) cytotoxicity of both surfactants in all tested concentrations.

Keywords

Cytotoxicity; Cell metabolic activity; Human osteoblasts; Hyaluronan; Surfactant; CTAB; Septonex

RIV year

2015

Released

17.07.2015

Publisher

Elsevier

Pages from

155

Pages to

161

Pages count

7

BibTex


@article{BUT115957,
  author="Pavlína {Sauerová} and Martina {Verdánová} and Tereza {Pilgrová} and Tereza {Venerová} and Filip {Mravec} and Marie {Kalbáčová} and Miloslav {Pekař}",
  title="Hyaluronic acid as a modulator of the cytotoxic effects of cationic surfactants",
  annote="This work reported results of the study of colloidal complexes of CTAB or Septonex with oppositely charged hyaluronic acid (HyA), based primarily on electrostatic interactions, which were prepared with the aim to test potential modulation of surfactants cytotoxic effects. Data show that CTAB–HyA or Septonex–HyA complexes reduce (in different rate according to the used surfactant and HyA concentrations) cytotoxicity of both surfactants in all tested concentrations.",
  address="Elsevier",
  chapter="115957",
  doi="10.1016/j.colsurfa.2015.06.058",
  howpublished="online",
  institution="Elsevier",
  number="1",
  volume="483",
  year="2015",
  month="july",
  pages="155--161",
  publisher="Elsevier",
  type="journal article in Web of Science"
}