Publication detail

Differential Analysis of Neurodegenerative Aging-Related Mitochondrial Genes of Long-Lived Naked Mole-Rat

ABO KHAYAL, L. PROVAZNÍK, I. TKACZ, E.

Original Title

Differential Analysis of Neurodegenerative Aging-Related Mitochondrial Genes of Long-Lived Naked Mole-Rat

English Title

Differential Analysis of Neurodegenerative Aging-Related Mitochondrial Genes of Long-Lived Naked Mole-Rat

Type

journal article - other

Language

en

Original Abstract

Analyzing the differential genetic traits related to senescence of the long-lived naked mole-rat and various species that are convergent phylogenetically, by a combination of bioinformatic algorithms with nucleotide genomic signal processing, and hierarchical cluster methods. Since the naked mole-rat has distinctive aging resistance, comparing the aging-related genes may guide to essential differences in pathological incidences of aging diseases among the species concerned.

English abstract

Analyzing the differential genetic traits related to senescence of the long-lived naked mole-rat and various species that are convergent phylogenetically, by a combination of bioinformatic algorithms with nucleotide genomic signal processing, and hierarchical cluster methods. Since the naked mole-rat has distinctive aging resistance, comparing the aging-related genes may guide to essential differences in pathological incidences of aging diseases among the species concerned.

Keywords

Aging-related genes, DNA damage, neurodegenerative diseases, naked mole-rat (Heterocephalus glaber).

RIV year

2013

Released

19.02.2013

Publisher

IACSIT Press

Location

Italy, Rome

Pages from

75

Pages to

79

Pages count

5

BibTex


@article{BUT97993,
  author="Layal {Abo Khayal} and Ivo {Provazník} and Ewaryst {Tkacz}",
  title="Differential Analysis of Neurodegenerative Aging-Related Mitochondrial Genes of Long-Lived Naked Mole-Rat",
  annote="Analyzing the differential genetic traits related to senescence of the long-lived naked mole-rat and various species that are convergent phylogenetically, by a combination of bioinformatic algorithms with nucleotide genomic signal processing, and hierarchical cluster methods. Since the naked mole-rat has distinctive aging resistance, comparing the aging-related genes may guide to essential differences in pathological incidences of aging diseases among the species concerned.",
  address="IACSIT Press",
  chapter="97993",
  doi="10.7763/IJBBB.2013.V3.168",
  howpublished="print",
  institution="IACSIT Press",
  number="2",
  volume="3",
  year="2013",
  month="february",
  pages="75--79",
  publisher="IACSIT Press",
  type="journal article - other"
}