Publication detail

SELECTION OF NANOPRTICLES FOR GENE AND PROTEIN DELIVERY AND QUANTIFICATION OF LASMID/PROTEIN SURFACE ADSORPTION

SKOPALÍK, J. HORÁK, T. ČMIEL, V.PARÁK, T. PRŮCHA, J. SVIK, K. MAŠEK, J.

Original Title

SELECTION OF NANOPRTICLES FOR GENE AND PROTEIN DELIVERY AND QUANTIFICATION OF LASMID/PROTEIN SURFACE ADSORPTION

English Title

SELECTION OF NANOPRTICLES FOR GENE AND PROTEIN DELIVERY AND QUANTIFICATION OF LASMID/PROTEIN SURFACE ADSORPTION

Language

en

Original Abstract

The surface charge of liposomes is an important parameter affecting electrostatic interactions between liposomes and surrounding molecules, particles and surfaces. The liposoms are traditional synthesized by thin-lipid film generating consistent particle size, with positive zeta potential and high pDNA encapsulation efficiency. However the effectvity of pDNA absoption is determined not only by surface properties of liposoms, however also by surronding solution and temperature. Liposoms-pDNA complexes can be a safe and non-invasive approach to transfect endothelial and muscle cells, with high potential in medicine

English abstract

The surface charge of liposomes is an important parameter affecting electrostatic interactions between liposomes and surrounding molecules, particles and surfaces. The liposoms are traditional synthesized by thin-lipid film generating consistent particle size, with positive zeta potential and high pDNA encapsulation efficiency. However the effectvity of pDNA absoption is determined not only by surface properties of liposoms, however also by surronding solution and temperature. Liposoms-pDNA complexes can be a safe and non-invasive approach to transfect endothelial and muscle cells, with high potential in medicine

Keywords

nanoparticles, protein delivery

Released

01.10.2020

Publisher

MUNI Press

Location

Brno

ISBN

978-80-210-9655-4

Book

XX. Workshop of Biophysical Chemists and Electrochemists Book of abstracts

Pages from

60

Pages to

61

Pages count

2

Documents

BibTex


@inproceedings{BUT167669,
  author="Josef {Skopalík} and Tomáš {Horák} and Vratislav {Čmiel}",
  title="SELECTION OF NANOPRTICLES FOR GENE AND PROTEIN DELIVERY AND QUANTIFICATION OF LASMID/PROTEIN
SURFACE ADSORPTION",
  annote="The surface charge of liposomes is an important parameter affecting electrostatic interactions
between liposomes and surrounding molecules, particles and surfaces. The liposoms are
traditional synthesized by thin-lipid film generating consistent particle size, with positive zeta
potential and high pDNA encapsulation efficiency. However the effectvity of pDNA absoption
is determined not only by surface properties of liposoms, however also by surronding solution
and temperature. Liposoms-pDNA complexes can be a safe and non-invasive approach to
transfect endothelial and muscle cells, with high potential in medicine",
  address="MUNI Press",
  booktitle="XX. Workshop of Biophysical Chemists and Electrochemists
Book of abstracts",
  chapter="167669",
  howpublished="online",
  institution="MUNI Press",
  year="2020",
  month="october",
  pages="60--61",
  publisher="MUNI Press"
}