Publication detail

The effect of selenium nanoparticles on antibacterial and cellular properties of titania nanotubes

BÍLEK, O. FOHLEROVÁ, Z.

Original Title

The effect of selenium nanoparticles on antibacterial and cellular properties of titania nanotubes

Type

abstract

Language

English

Original Abstract

To date, most of the materials used in tissue engineering such as titanium and its alloys suffer from the susceptibility to bacterial infections. The potential use of antimicrobial nanoparticles can make the material less susceptible to formation of biofilm, which could lead to increased success rate of individual applications. In our work we prepared TiO2 nanotubes via anodic oxidation in organic electrolyte containing ethylene glycol, ammonium fluoride and water. As a substrate we used thin titanium film with thickness of 500nm deposited onto 4-inch p-type silicon wafer covered by 500nm of thermal silicon dioxide. Anodic oxidation resulted in nanotubular surface with nanotube diameter of approximately 50 nanometers. To convert fabricated TiO2 nanotubes from amorphous to crystalline state, they were annealed at 450 °C for 3 hours. The annealed samples were further decorated with various concentrations of chemically synthesized selenium nanoparticles. Selenium nanoparticles were prepared by the reaction of glutathione and sodium selenite in water. Products of the reaction were spherical selenium nanoparticles with the diameter of approximately 80 nm. Modified surfaces were consequently evaluated in terms of antibacterial and cellular properties. Antibacterial activity was tested by the test of viability of E.Coli after the interaction with nanostructured surface. Cellular tests utilized MG-63 cells and were focused on adhesion and proliferation. More research needs to be done, however according to results gained so far, this modification could influence the implant acceptance in both orthopedic and dental implant applications.

Keywords

titanium dioxide; nanotube; selenium nanoparticle; antibacterial properties

Authors

BÍLEK, O.; FOHLEROVÁ, Z.

Released

27. 4. 2018

Publisher

Masaryk University

Location

Žerotínovo nám. 617/9, 601 77 Brno, Czech Republic

ISBN

ISBN 978-80-210-8943

Book

CEITEC PhD & Posdoc Retreat Telč 26-27 April 2018 Book of Abstracts

Edition

1

BibTex

@misc{BUT151594,
  author="Ondřej {Bílek} and Zdenka {Fohlerová}",
  title="The effect of selenium nanoparticles on antibacterial and cellular
properties of titania nanotubes",
  booktitle="CEITEC PhD & Posdoc Retreat
Telč 26-27 April 2018
Book of Abstracts",
  year="2018",
  series="1",
  pages="114",
  publisher="Masaryk University",
  address="Žerotínovo nám. 617/9, 601 77 Brno, Czech Republic",
  isbn="ISBN 978-80-210-8943",
  note="abstract"
}