Publication detail

Physical, mechanical, and biological properties of electrophoretically deposited lithium-doped calcium phosphates

DRDLÍK, D. SLÁMA, M. HADRABA, H. DRDLÍKOVÁ, K. CIHLÁŘ, J.

Original Title

Physical, mechanical, and biological properties of electrophoretically deposited lithium-doped calcium phosphates

Type

journal article in Web of Science

Language

English

Original Abstract

In the present work, the preparation of sintered lithium-doped tricalcium phosphates was studied, along with their physical, mechanical, and biological properties. Calcium phosphates were shaped via the use of electrophoretic deposition (EPD), using colloidally milled dispersions of hydroxyapatite (HAp) particles. The dispersions were stabilised with monochloroacetic acid. Lithium was incorporated into the structure via an addition of lithium chloride, which also served to optimise the deposition process. The dispersions were milled colloidally for periods of 0-48 h. The colloidal milling resulted in two effects: i) disintegration of the commercial HAp powder (10 mu m) agglomerates, ii) unimodal distribution of the HAp particles ( similar to 170 nm). The fine particles of the milled HAp dispersions accelerated the deposition rate, and increased the mass of the deposit. The reduced size of the initial particles, owed to the milling, led to the superior arrangement of the particles during deposition and to reduced porosity after sintering (1050-1250 degrees C). The HAp decomposed into tricalcium phosphate phases during sintering. At a sintering temperature of 1250 degrees C, grain growth occurred, which consequently resulted in a slight degradation of the mechanical properties (reduction in hardness and Young's modulus). In contrast, the hardness and Young's modulus increased as the dispersion milling time increased (smaller grain size after sintering); however, the fracture toughness did not change. The results of the biological testing confirmed the bioactivity of the material through the growth of the apatite layer in the simulated body fluid (SBF), and the biodegradation of the prepared materials in the Tris-HCI solution. With regard to the preparation of compact lithium-doped tricalcium phosphates, the best results were obtained in the case of the sample that utilised the dispersion that was milled for 48 h, and was sintered at 1050 degrees C.

Keywords

Lithium; Calcium phosphate; Colloidal milling; Electrophoretic deposition; Material properties

Authors

DRDLÍK, D.; SLÁMA, M.; HADRABA, H.; DRDLÍKOVÁ, K.; CIHLÁŘ, J.

Released

15. 2. 2018

Publisher

Elsevier

ISBN

0272-8842

Periodical

Ceramics International

Year of study

44

Number

3

State

United Kingdom of Great Britain and Northern Ireland

Pages from

2884

Pages to

2891

Pages count

8

URL

http://www.sciencedirect.com/science/article/pii/S0272884217324781

BibTex

@article{BUT142649,
  author="Daniel {Drdlík} and Martin {Sláma} and Hynek {Hadraba} and Katarina {Drdlíková} and Jaroslav {Cihlář}",
  title="Physical, mechanical, and biological properties of electrophoretically deposited lithium-doped calcium phosphates",
  journal="Ceramics International",
  year="2018",
  volume="44",
  number="3",
  pages="2884--2891",
  doi="10.1016/j.ceramint.2017.11.035",
  issn="0272-8842",
  url="http://www.sciencedirect.com/science/article/pii/S0272884217324781"
}