Publication detail

Terahertz time-domain spectroscopy for studying the kinetics of tissue adhesives

NEDVĚDOVÁ, M. KŘESÁLEK, V. ADAMÍK, Z. PROVAZNÍK, I.

Original Title

Terahertz time-domain spectroscopy for studying the kinetics of tissue adhesives

Czech Title

Terahertzová spektroskopie pro studium kinetiky tkáňových lepidel

English Title

Terahertz time-domain spectroscopy for studying the kinetics of tissue adhesives

Type

conference paper

Language

en

Original Abstract

This study deals with the kinetics of tissue adhesives used for supporting the hemostasis and wound closure during surgical intervention. There are several types of adhesives of different composition which is closely related with their application. The time of curing plays an important role because some applications may require very fast glue for prompt vessel or wound closure; conversely some situations need slower solidification because of longer manipulation with the glue during surgery. Here, the terahertz time-domain spectroscopy is used for studying the kinetics of the glues. To slow the reaction rate, an oily substance is added to the glue samples. The technique of attenuated total reflection is used in this application; the defined amount of glue sample or its mixture is applied on the silicon crystal and the terahertz response is measured in time. This time dependences are analyzed to find time constants for mathematical description of the glue kinetics.

Czech abstract

Tato studie se zabývá kinetikou tkáňových lepidel používaných pro podporu hemostázy a uzavření rány v průběhu chirurgického zákroku. Existuje několik typů lepidel různého složení, které úzce souvisí s jejich konkrétní aplikací. Doba vytvrzování hraje důležitou roli, protože některé aplikace mohou vyžadovat velmi rychlé lepidlo pro rychlé uzavření cévy nebo rány; naopak v některých situacích je třeba tuhnutí zpomalit kvůli delší manipulaci s lepidlem v průběhu chirurgického zákroku. Právě pro studium kinetiky lepidel je zde použita metoda terahertzové spektroskopie v časové doméně. Pro zpomalení rychlosti reakce je do vzorku lepidla přidána látka na olejové bázi. Pro tuto aplikaci je použita technika zeslabeného úplného odrazu; definované množství vzorku lepidla nebo jeho směsi se nanese na křemíkový krystal a terahertzová odezva je měřena v čase. Tyto časové závislostí jsou analyzovány s cílem najít časové konstanty pro matematický popis kinetiky lepidla.

English abstract

This study deals with the kinetics of tissue adhesives used for supporting the hemostasis and wound closure during surgical intervention. There are several types of adhesives of different composition which is closely related with their application. The time of curing plays an important role because some applications may require very fast glue for prompt vessel or wound closure; conversely some situations need slower solidification because of longer manipulation with the glue during surgery. Here, the terahertz time-domain spectroscopy is used for studying the kinetics of the glues. To slow the reaction rate, an oily substance is added to the glue samples. The technique of attenuated total reflection is used in this application; the defined amount of glue sample or its mixture is applied on the silicon crystal and the terahertz response is measured in time. This time dependences are analyzed to find time constants for mathematical description of the glue kinetics.

Keywords

glue kinetics, oil, terahertz time-domain spectroscopy, tissue adhesive

RIV year

2015

Released

22.09.2015

Publisher

SPIE

Location

Washington

ISBN

9781628418613

Book

Proc. SPIE 9651, Millimetre Wave and Terahertz Sensors and Technology VIII

Pages from

9

Pages to

16

Pages count

8

URL

BibTex


@inproceedings{BUT119995,
  author="Marie {Nedvědová} and Vojtěch {Křesálek} and Zdeněk {Adamík} and Ivo {Provazník}",
  title="Terahertz time-domain spectroscopy for studying the kinetics of tissue adhesives",
  annote="This study deals with the kinetics of tissue adhesives used for supporting the hemostasis and wound closure during surgical intervention. There are several types of adhesives of different composition which is closely related with their application. The time of curing plays an important role because some applications may require very fast glue for prompt vessel or wound closure; conversely some situations need slower solidification because of longer manipulation with the glue during surgery. Here, the terahertz time-domain spectroscopy is used for studying the kinetics of the glues. To slow the reaction rate, an oily substance is added to the glue samples. The technique of attenuated total reflection is used in this application; the defined amount of glue sample or its mixture is applied on the silicon crystal and the terahertz response is measured in time. This time dependences are analyzed to find time constants for mathematical description of the glue kinetics.",
  address="SPIE",
  booktitle="Proc. SPIE 9651, Millimetre Wave and Terahertz Sensors and Technology VIII",
  chapter="119995",
  doi="10.1117/12.2194584",
  howpublished="print",
  institution="SPIE",
  year="2015",
  month="september",
  pages="9--16",
  publisher="SPIE",
  type="conference paper"
}