Detail publikace

Gene Ontology Driven Feature Filtering from Microarray Data

ŠILHAVÁ, J. SMRŽ, P.

Originální název

Gene Ontology Driven Feature Filtering from Microarray Data

Anglický název

Gene Ontology Driven Feature Filtering from Microarray Data

Typ

článek ve sborníku mimo WoS a Scopus

Jazyk

čeština

Originální abstrakt

Microarray data is high-dimensional and noisy. Dimension reduction, i.e. selecting a small number of genes, is an effective way to improve mining efficiency. We propose a novel approach that integrates gene ontology knowledge at the level of feature selection into microarray data to improve binary class prediction. The advantage of this filtering approach lies in considering gene-to-gene relations and selecting more meaningful features comparing to the methods evaluating genes in isolation. In addition, gene ontology knowledge can overcome the limitations of noisy microarray data. Our approach is evaluated on a real benchmark dataset.

Anglický abstrakt

Microarray data is high-dimensional and noisy. Dimension reduction, i.e. selecting a small number of genes, is an effective way to improve mining efficiency. We propose a novel approach that integrates gene ontology knowledge at the level of feature selection into microarray data to improve binary class prediction. The advantage of this filtering approach lies in considering gene-to-gene relations and selecting more meaningful features comparing to the methods evaluating genes in isolation. In addition, gene ontology knowledge can overcome the limitations of noisy microarray data. Our approach is evaluated on a real benchmark dataset.

Klíčová slova v angličtině

feature selection, gene ontology, microarray data, class prediction

Autoři

ŠILHAVÁ, J.; SMRŽ, P.

Rok RIV

2010

Vydáno

1. 1. 2010

Místo

Jindřichův Hradec

ISBN

978-80-245-1636-3

Kniha

Znalosti 2010

Edice

9th Annual Conference, Jindřichův Hradec

Strany od

263

Strany do

266

Strany počet

4

BibTex

@inproceedings{BUT30857,
  author="Jana {Šilhavá} and Pavel {Smrž}",
  title="Gene Ontology Driven Feature Filtering from Microarray Data",
  booktitle="Znalosti 2010",
  year="2010",
  series="9th Annual Conference, Jindřichův Hradec",
  pages="263--266",
  address="Jindřichův Hradec",
  isbn="978-80-245-1636-3"
}