Detail publikace

Pharmaceutical and narcotics monitoring in Brno wastewater system and estimation of seasonal effect on the abuse of illicit drugs by a wastewater-based epidemiology approach

CARNEVALE MIINO, M. MACSEK, T. HALEŠOVÁ, T. CHORAZY, T. HLAVÍNEK, P.

Originální název

Pharmaceutical and narcotics monitoring in Brno wastewater system and estimation of seasonal effect on the abuse of illicit drugs by a wastewater-based epidemiology approach

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

The presence of pharmaceuticals (PHA) and narcotics (NAR) in wastewater (WW) has attracting growing interest due to concern for aquatic environment and the possibility to exploit their presence to estimate drug consumption by population. This work aims to (i) quantify PHA and NAR in the WW of the Brno metropolitan area, (ii) determine the effectiveness of the current conventional wastewater treatment plant (WWTP), and (iii) estimate the illicit drug (ID) consumption. 23 PHA and 9 NAR were frequently detected in the untreated WW and studied for their removal. One year monitoring was carried out to highlight a possible seasonal pattern with PHA and NAR load in WW, WWTP effectiveness, and illicit consumption. Results highlighted that the most abundant PHA and NAR were caffeine (73.9 ± 6.9 μg L−1) and methamphetamine (2.3 ± 0.1 μg L−1) while oxazepam (0.13 ± 0.05 μg L−1) and EDDP (0.02 ± 0.01 μg L−1) were the lowest ones, respectively. Only paracetamol, caffeine, atenolol, ciprofloxacin, amphetamine, cocaine, morphine, and benzoylecgonine exhibited a high biodegradability being removed almost completely (> 90 %). A predominant illicit use of methamphetamine was estimated (17 ± 0.6 doses 1000.inh−1 d−1) that might suggest a higher number of consumers than previous official estimation. A lower abuse of cocaine (2.7 ± 0.5 doses 1000.inh−1 d−1), amphetamine (2.2 ± 0.3 doses 1000.inh−1 d−1), methadone (1.1 ± 0.2 doses 1000.inh−1 d−1), heroin (0.9 ± 0.2 doses 1000.inh−1 d−1), and MDMA (0.7 ± 0.1 doses 1000.inh−1 d−1) was found. A seasonality pattern was highlighted for some PHA and NAR influent load and removal, and, about ID consumption, only for heroin and methadone. These results will be useful for water utilities, to enhance the knowledge about the presence and removal of PHA and NAR, and local and national authorities to evaluate and counteract the problem of ID abuse.

Klíčová slova

WBE; emerging contaminants; pharmaceutical compounds removal; pervitine; environmental surveillance; public health

Autoři

CARNEVALE MIINO, M.; MACSEK, T.; HALEŠOVÁ, T.; CHORAZY, T.; HLAVÍNEK, P.

Vydáno

30. 5. 2023

Nakladatel

Elsevier B.V.

Místo

Amsterdam, The Netherlands

ISSN

0048-9697

Periodikum

Science of the Total Environment

Číslo

164386

Stát

Nizozemsko

Strany od

1

Strany do

35

Strany počet

35

URL

https://www.sciencedirect.com/science/article/pii/S0048969723030073?via%3Dihub

BibTex

@article{BUT183707,
  author="Marco {Carnevale Miino} and Tomáš {Macsek} and Taťána {Halešová} and Tomáš {Chorazy} and Petr {Hlavínek}",
  title="Pharmaceutical and narcotics monitoring in Brno wastewater system and estimation of seasonal effect on the abuse of illicit drugs by a wastewater-based epidemiology approach",
  journal="Science of the Total Environment",
  year="2023",
  number="164386",
  pages="35",
  doi="10.1016/j.scitotenv.2023.164386",
  issn="0048-9697",
  url="https://www.sciencedirect.com/science/article/pii/S0048969723030073?via%3Dihub"
}