Detail publikace

Imaging of Biological Tissues

POŘÍZKA, P. MODLITBOVÁ, P. KAISER, J.

Originální název

Imaging of Biological Tissues

Typ

kapitola v knize

Jazyk

angličtina

Originální abstrakt

Laser-Induced Breakdown Spectroscopy (LIBS) has established its position as a method for the analysis of biological samples. We aim to introduce the benefits of LIBS for the qualitative elemental imaging of tissues. The state-of-the-art instrumentation enables elemental imaging of sample surfaces with a high resolution (down to micro-scale) on a large scale (up to a whole-slide image), i.e., megapixel imaging of the distribution of investigated elements. The implementation of this promising tool to the analytical pipeline in various fields (from developmental biology to clinical research) is discussed. The typical interpretation of LIBS results through basic spectroscopic algorithms and machine learning is dissected. The chapter reviews recent advances of LIBS namely in soft and hard tissue analyses when the detection of endogenous and exogenous elements (major and trace metals) is concerned. The comparison to other elemental imaging methods (namely Laser Ablation Inductively Coupled Plasma Mass Spectrometry) is given. Finally, future perspectives and development of LIBS bioimaging is suggested.

Klíčová slova

Laser-Induced Breakdown Spectroscopy (LIBS)

Autoři

POŘÍZKA, P.; MODLITBOVÁ, P.; KAISER, J.

Vydáno

13. 12. 2022

ISBN

978-3-031-14502-5

Kniha

Laser-Induced Breakdown Spectroscopy in Biological, Forensic and Materials Sciences

Strany počet

26

URL

https://link.springer.com/chapter/10.1007/978-3-031-14502-5_6

BibTex

@inbook{BUT183026,
  author="Pavel {Pořízka} and Pavlína {Modlitbová} and Jozef {Kaiser}",
  title="Imaging of Biological Tissues",
  booktitle="Laser-Induced Breakdown Spectroscopy in Biological, Forensic and Materials Sciences",
  year="2022",
  pages="26",
  doi="10.1007/978-3-031-14502-5\{_}6",
  isbn="978-3-031-14502-5",
  url="https://link.springer.com/chapter/10.1007/978-3-031-14502-5_6"
}