Detail publikace

MICRO-FLUIDIC SYSTEM WITH GROOVED POLE PIECES OF MAGNETIC CIRCUIT

Originální název

MICRO-FLUIDIC SYSTEM WITH GROOVED POLE PIECES OF MAGNETIC CIRCUIT

Anglický název

MICRO-FLUIDIC SYSTEM WITH GROOVED POLE PIECES OF MAGNETIC CIRCUIT

Jazyk

en

Originální abstrakt

Micro-fluidic systems are used in approximately 30 years for detect or separate biological molecules which are contain in a biological medium (blood, serum, etc.). The technique of separation is based on magnetic force acting on the magnetic particles which are added to the medium. One way to increase separation efficiency is to optimize the magnetic circuit. Two versions of magnetic circuit for the micro-fluidic system are designed, tested and compared in this study. The first of them has solid pole pieces (without grooves), the second one is provided with grooves which are oriented perpendicular to the direction of a fluid flow through the system. A suitable geometry of the grooves was chosen using a FEM model which is verified by measurement. Hypothesis that the grooved pole pieces ensure higher amount of captured particles in the system in comparison with the case of solid pole pieces was confirmed. But, the comparison of the captured particles amount was made just visually. Therefore, the amount of particles which are washout during a flow test should be evaluated by more quantifiable method in future study, for example using Beer-Lambert law.

Anglický abstrakt

Micro-fluidic systems are used in approximately 30 years for detect or separate biological molecules which are contain in a biological medium (blood, serum, etc.). The technique of separation is based on magnetic force acting on the magnetic particles which are added to the medium. One way to increase separation efficiency is to optimize the magnetic circuit. Two versions of magnetic circuit for the micro-fluidic system are designed, tested and compared in this study. The first of them has solid pole pieces (without grooves), the second one is provided with grooves which are oriented perpendicular to the direction of a fluid flow through the system. A suitable geometry of the grooves was chosen using a FEM model which is verified by measurement. Hypothesis that the grooved pole pieces ensure higher amount of captured particles in the system in comparison with the case of solid pole pieces was confirmed. But, the comparison of the captured particles amount was made just visually. Therefore, the amount of particles which are washout during a flow test should be evaluated by more quantifiable method in future study, for example using Beer-Lambert law.

BibTex


@inproceedings{BUT151987,
  author="Ondřej {Macháček} and Michal {Kubík} and Jakub {Roupec} and Zbyněk {Strecker} and Ivan {Mazůrek}",
  title="MICRO-FLUIDIC SYSTEM WITH GROOVED POLE PIECES OF MAGNETIC CIRCUIT",
  annote="Micro-fluidic systems are used in approximately 30 years for detect or separate biological
molecules which are contain in a biological medium (blood, serum, etc.). The technique of separation is based
on magnetic force acting on the magnetic particles which are added to the medium. One way to increase
separation efficiency is to optimize the magnetic circuit. Two versions of magnetic circuit for the micro-fluidic
system are designed, tested and compared in this study. The first of them has solid pole pieces (without
grooves), the second one is provided with grooves which are oriented perpendicular to the direction of a fluid
flow through the system. A suitable geometry of the grooves was chosen using a FEM model which is verified
by measurement. Hypothesis that the grooved pole pieces ensure higher amount of captured particles in the
system in comparison with the case of solid pole pieces was confirmed. But, the comparison of the captured
particles amount was made just visually. Therefore, the amount of particles which are washout during a flow
test should be evaluated by more quantifiable method in future study, for example using Beer-Lambert law.",
  address="Institute of Theoretical and Applied Mechanics of the Czech Academy of Sciences",
  booktitle="ENGINEERING MECHANICS 2018",
  chapter="151987",
  edition="24th INTERNATIONAL CONFERENCE",
  howpublished="print",
  institution="Institute of Theoretical and Applied Mechanics of the Czech Academy of Sciences",
  number="1",
  year="2018",
  month="may",
  pages="521--524",
  publisher="Institute of Theoretical and Applied Mechanics of the Czech Academy of Sciences",
  type="conference paper"
}