Detail publikace

Clustering Techniques for Protein Fragments Analysis

Originální název

Clustering Techniques for Protein Fragments Analysis

Anglický název

Clustering Techniques for Protein Fragments Analysis

Jazyk

en

Originální abstrakt

This book presents a novel method for clustering of protein substructures that we developed in order to study the relationships between protein sequences and their structure. We show some properties of this method and the experimental results obtained by analyzing real data from PDB (Protein Data Bank). Furthermore, we present the results of the comparison of our method and the most commonly used methods for clustering of protein structures. The main advantage of our method is its high efficiency and scalability, which are key factors for analyzing large data sets. Finally, we propose a procedure for finding sequence profiles that tend to occur in more than one structural conformation but the number of their structural conformations is limited. This procedure is based on our method for protein substructure clustering.

Anglický abstrakt

This book presents a novel method for clustering of protein substructures that we developed in order to study the relationships between protein sequences and their structure. We show some properties of this method and the experimental results obtained by analyzing real data from PDB (Protein Data Bank). Furthermore, we present the results of the comparison of our method and the most commonly used methods for clustering of protein structures. The main advantage of our method is its high efficiency and scalability, which are key factors for analyzing large data sets. Finally, we propose a procedure for finding sequence profiles that tend to occur in more than one structural conformation but the number of their structural conformations is limited. This procedure is based on our method for protein substructure clustering.

BibTex


@book{BUT62045,
  author="Ivana {Burgetová} and Jaroslav {Zendulka} and Matej {Lexa}",
  title="Clustering Techniques for Protein Fragments Analysis",
  annote="This book presents a novel method for clustering of protein substructures that we
developed in order to study the relationships between protein sequences and their
structure. We show some properties of this method and the experimental results
obtained by analyzing real data from PDB (Protein Data Bank). Furthermore, we
present the results of the comparison of our method and the most commonly used
methods for clustering of protein structures. The main advantage of our method is
its high efficiency and scalability, which are key factors for analyzing large
data sets. Finally, we propose a procedure for finding sequence profiles that
tend to occur in more than one structural conformation but the number of their
structural conformations is limited. This procedure is based on our method for
protein substructure clustering.",
  address="Faculty of Information Technology BUT",
  chapter="62045",
  edition="NEUVEDEN",
  howpublished="print",
  institution="Faculty of Information Technology BUT",
  year="2010",
  month="december",
  pages="0--0",
  publisher="Faculty of Information Technology BUT",
  type="book"
}