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Detail publikace
Göçtü, Y. Oral, CM. Ercan, B.
Originální název
Selenite-Incorporated Amorphous Calcium-Magnesium Carbonate Nanoparticles Reduce Bacterial Growth
Typ
článek v časopise ve Web of Science, Jimp
Jazyk
angličtina
Originální abstrakt
Amorphous calcium carbonate (ACC) is a nontoxic and degradable nanomaterial. ACC can be synthesized using the coprecipitation technique, which enables the incorporation of ions into its amorphous structure. Although ACC has been investigated for various applications, such as wastewater treatment, in vivo imaging, and drug delivery, its antibacterial properties have not been explored. Considering the extraordinary capability of bacteria to adapt antimicrobial strategies, as well as the extensive burden of bacteria-induced problems on healthcare systems and the world economy, the need for effective antibacterial agents is becoming a pressing issue. Herein, we introduced selenite-incorporated magnesium-stabilized amorphous calcium carbonate (ACMC) nanoparticles as a sustainable antibacterial material. For the first time, we demonstrated that selenite ions could be incorporated into ACMC nanoparticles while preserving the amorphous structure. Antibacterial activity analysis showed that selenite-incorporated ACMC (Se-ACMC) nanoparticles at 1 g/L concentration could significantly reduce the growth of Gram-positive (Staphylococcus aureus and Staphylococcus epidermidis) and Gram-negative (Escherichia coli and Pseudomonas aeruginosa) bacteria strains within 24 h of interaction. As an important observation, even the lowest selenite incorporation (4.38 +/- 0.19 mg selenium per g of nanoparticles) led to a more than 3-log reduction in the number of S. epidermidis colonies. Additionally, the antibacterial activity was enhanced with an increase in the amount of incorporated selenite. These results indicated that ion-incorporated ACMC nanoparticles can pave the way for applications as antibacterial agents.
Klíčová slova
CaCO3; amorphous; ion incorporation; stabilization; antibacterial
Autoři
Göçtü, Y.; Oral, CM.; Ercan, B.
Vydáno
12. 9. 2023
Nakladatel
American Chemical Society
Místo
WASHINGTON
ISSN
2574-0970
Periodikum
ACS Applied Nano Materials
Ročník
6
Číslo
18
Stát
Spojené státy americké
Strany od
16286
Strany do
16296
Strany počet
11
URL
https://pubs.acs.org/doi/10.1021/acsanm.3c02415
Plný text v Digitální knihovně
http://hdl.handle.net/11012/245057
BibTex
@article{BUT187332, author="Yağmur {Göçtü} and Çaǧatay Mert {Oral} and Batur {Ercan}", title="Selenite-Incorporated Amorphous Calcium-Magnesium Carbonate Nanoparticles Reduce Bacterial Growth", journal="ACS Applied Nano Materials", year="2023", volume="6", number="18", pages="16286--16296", doi="10.1021/acsanm.3c02415", issn="2574-0970", url="https://pubs.acs.org/doi/10.1021/acsanm.3c02415" }