Detail publikace

Nanomaterials with active targeting as advanced antimicrobials

ŠMERKOVÁ, K. DOLEŽELÍKOVÁ, K. BOZDĚCHOVÁ, L. HEGER, Z. ŽŮREK, L. ADAM, V.

Originální název

Nanomaterials with active targeting as advanced antimicrobials

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

With a growing health threat of bacterial resistance to antibiotics, the nanomaterials have been extensively studied as an alternative. It is assumed that antimicrobial nanomaterials can affect bacteria by several mechanisms simultaneously and thereby overcome antibiotic resistance. Another promising potential use is employing nanomaterials as nanocarriers for antibiotics in order to overcome bacterial defense mechanisms. The passive targeting of nanomaterials is the often used strategy for bacterial treatment, including intracellular infections of macrophages. Furthermore, the specific targeting enhances the efficacy of antimicrobials and reduces side effects. This review aims to discuss advantages, disadvantages, and challenges of nanomaterials in the context of the targeting strategies for antimicrobials as advanced tools for treatments of bacterial infections.

Klíčová slova

biomimetic; delivery; nanomedicine; peptide; resistance

Autoři

ŠMERKOVÁ, K.; DOLEŽELÍKOVÁ, K.; BOZDĚCHOVÁ, L.; HEGER, Z.; ŽŮREK, L.; ADAM, V.

Vydáno

25. 5. 2020

ISSN

1939-5116

Periodikum

WIRES NANOMED NANOBI

Číslo

e1636

Stát

Spojené státy americké

Strany od

1

Strany do

25

Strany počet

25

URL

https://doi.org/10.1002/wnan.1636

BibTex

@article{BUT164053,
  author="Kristýna {Šmerková} and Kristýna {Doleželíková} and Lucie {Bozděchová} and Zbyněk {Heger} and Luděk {Žůrek} and Vojtěch {Adam}",
  title="Nanomaterials with active targeting as advanced antimicrobials",
  journal="WIRES NANOMED NANOBI",
  year="2020",
  number="e1636",
  pages="1--25",
  doi="10.1002/wnan.1636",
  issn="1939-5116",
  url="https://doi.org/10.1002/wnan.1636"
}