Detail publikace

Effect of the selected phenolic and flavonoid compounds of black pepper and caraway seeds on prostate cells

LACKOVÁ, Z. BUCHTELOVÁ, H. BUCHTOVÁ, Ž. ADAM, V. ZÍTKA, O.

Originální název

Effect of the selected phenolic and flavonoid compounds of black pepper and caraway seeds on prostate cells

Typ

článek ve sborníku ve WoS nebo Scopus

Jazyk

angličtina

Originální abstrakt

In this study, the effect of selected phenolic and flavonoid compounds of black pepper and caraway seeds on prostate cells (PNT1A, 22RV1 and PC3) was observed. Synthetic standards of 3,4-dihydroxybenzaldehyde and naringenin chalcone, identified previously by HPLC-MS in black pepper seeds extracts, and neochlorogenic acid and apigenin, identified in caraway seeds extracts, were applied. For the evaluation of the potential inhibitory effect of selected compounds on PNT1A, 22RV1 and PC3 cells, the clonogenic assay and the microscopic observation of cells were done. The results of clonogenic assay showed that phenolic compounds had the strongest inhibitory effect on 22RV1 and PC3 cells, while the flavonoid compounds had the strongest inhibitory effect on PNT1A cells.

Klíčová slova

Spices; clonogenic assay; phenolic compounds; flavonoid compounds; prostate cell lines

Autoři

LACKOVÁ, Z.; BUCHTELOVÁ, H.; BUCHTOVÁ, Ž.; ADAM, V.; ZÍTKA, O.

Vydáno

31. 12. 2017

Nakladatel

Mendel University in Brno

ISBN

978-80-7509-529-9

Kniha

MendelNet 2017

Strany od

900

Strany do

904

Strany počet

5

URL

https://mendelnet.cz/artkey/mnt-201701-0103_Effect-of-the-selected-phenolic-and-flavonoid-compounds-of-black-pepper-and-caraway-seeds-on-prostate-cells.php?back=/magno/mnt/2017/mn1.php?secid=4

Plný text v Digitální knihovně

http://hdl.handle.net/11012/84188

BibTex

@inproceedings{BUT148746,
  author="Zuzana {Lacková} and Hana {Michálková} and Žaneta {Buchtová} and Vojtěch {Adam} and Ondřej {Zítka}",
  title="Effect of the selected phenolic and flavonoid compounds of black pepper and caraway seeds on prostate cells",
  booktitle="MendelNet 2017",
  year="2017",
  pages="900--904",
  publisher="Mendel University in Brno",
  isbn="978-80-7509-529-9",
  url="https://mendelnet.cz/artkey/mnt-201701-0103_Effect-of-the-selected-phenolic-and-flavonoid-compounds-of-black-pepper-and-caraway-seeds-on-prostate-cells.php?back=/magno/mnt/2017/mn1.php?secid=4"
}