Detail projektu

Photoacoustic/Ultrasound Mammoscopy for evaluating screening-detected lesions in the breast

Období řešení: 01.01.2017 — 31.12.2020

O projektu

PAMMOTH's objective is to develop, validate and begin exploitation of a dedicated breast imaging device for a significant impact in breast cancer diagnosis. The proposed device combines non-invasive 3D photoacoustic imaging and laser-induced ultrasound imaging. The device will provide near real-time, full-breast, multimodal images to the radiologist. From the ultrasound mode, the radiologist will visualize anatomical features and extent of tumors, and from multiwavelength photoacoustics, she will see tumor vascularity. Quantitative spectroscopic photoacoustic images will be extracted off-line, providing the radiologist information relating to tumor physiology and function such as angiogenesis and hypoxia. The choice of the relevant biological targets, and of the functionalities and technical principles applied in the PAMMOTH imager, will enable sensitive, accurate and quantitative measurements of these targets. This will provide relevant information to the radiologist to make accurate diagnosis with high specificity. We aim to make the imaging device such for all populations of women, with short time intervals between positive screening and diagnosis, having high through-put, possessing no carcinogenic potential and causing no pain and discomfort to patients.

Popis česky
Cílem projektu PAMMOTH je vyvinout, validovat a uvést do praxe nový přístroj pro neinvazivní screening prsou s cílem o včasnou diagnozu rakoviny prsou. Navržené zařízení kombinuje 3D fotoakustické snímkování a laserem indukované ultrazvukové snímkování. Cílem je dosáhnout vysoké přesnosti detekce v reálném čase.

Klíčová slova
photoacoustic imaging, laser-induced ultrasound, high performance computing, numerical methods, breast cancer

Označení

PAMMOTH

Originální jazyk

angličtina

Řešitelé

Jaroš Jiří, doc. Ing., Ph.D.
- hlavní řešitel (01.01.2017 - 31.12.2020)

Útvary

Ústav počítačových systémů
- spolupříjemce (18.04.2016 - 31.12.2020)
EKSPLA
- spolupříjemce (18.04.2016 - 31.12.2020)
Imasonic SAS
- spolupříjemce (18.04.2016 - 31.12.2020)
Medisch Spectrum Twente
- spolupříjemce (18.04.2016 - 31.12.2020)
PA Imaging Holding BV
- spolupříjemce (18.04.2016 - 31.12.2020)

Zdroje financování

Ministerstvo školství, mládeže a tělovýchovy ČR - Společná technologická iniciativa ECSEL
- plně financující (2017-01-01 - 2020-12-31)

Výsledky

JAROŠ, M.; TREEBY, B.; JAROŠ, J. Design of HIFU Treatment Plans using Evolutionary Strategy. In GECCO'18 Companion: Genetic and Evolutionary Computation Conference Companion. Kyoto: Association for Computing Machinery, 2018. p. 1568-1575. ISBN: 978-1-4503-5764-7.
Detail

KADLUBIAK, K.; JAROŠ, J.; TREEBY, B. GPU-accelerated Simulation of Elastic Wave Propagation. In The 2018 International Conference on High Performance Computing & Simulation (HPCS 2018). Orleans: IEEE Computer Society, 2018. p. 188-195. ISBN: 978-1-5386-7879-4.
Detail

JAROŠ, M.; TREEBY, B.; JAROŠ, J. k-Dispatch: A Management System for Biomedical Ultrasound Workflows in Personalized Medicine. In 2020. p. 0-0.
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VAVERKA, F.; TREEBY, B.; JAROŠ, J. Advancements in Ultrasound Simulations Enabled by High-bandwidth GPU Interconnects. Denver: 2019. p. 0-0.
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BORDOVSKÝ, G. Challenges In the Computer Photoacoustic Tomograpy Using the k-Wave Toolbox. In Počítačové architektúry & diagnostika PAD 2018. Plzeň: University of West Bohemia in Pilsen, 2018. p. 49-52. ISBN: 978-80-261-0814-6.
Detail

TREEBY, B.; VAVERKA, F.; JAROŠ, J. Performance and Accuracy Analysis of Nonlinear k-Wave Simulations Using Local Domain Decomposition with an 8-GPU Server. Proceedings of Meetings on Acoustics, 2018, vol. 34, no. 022002, p. 1-5. ISSN: 1939-800X.
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BORDOVSKÝ, G. Photoacoustic Reconstruction with Progressive Grid Refinement. Ostrava: 2019. p. 0-0.
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VAVERKA, F.; TREEBY, B.; JAROŠ, J. Evaluation of the Suitability of Intel Xeon Phi Clusters for the Simulation of Ultrasound Wave Propagation using Pseudospectral Methods. In 19th International Conference on Computational Science 2019, Faro, Portugal, June 12-14, 2019. Lecture Notes in Computer Science. Faro: Springer International Publishing, 2019. p. 577-590. ISBN: 978-3-030-22743-2.
Detail

MARTIN, E.; JAROŠ, J.; TREEBY, B. Experimental Validation of k-Wave: Nonlinear Wave Propagation in Layered, Absorbing Fluid Media. IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, 2020, vol. 67, no. 1, p. 81-91. ISSN: 1525-8955.
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JAROŠ, M.; TREEBY, B.; JAROŠ, J. Scientific workflow management framework. Soláň: 2019. p. 1 (1 s.).
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BORDOVSKÝ, G.; JAROŠ, J. On the Complexity of Photoacoustic Tomography: A Trade-off Between Image Quality and Computational Cost. Solaň: 2019. p. 1 (1 s.).
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JAROŠ, M.; JAROŠ, J.; TREEBY, B. Adaptive Execution Planning in Workflow Management Systems. Denver: 2019. p. 0-0.
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JAROŠ, M.; TREEBY, B.; JAROŠ, J. Adaptive Execution Planning in Biomedical Workflow Management Systems. Ostrava: 2019. p. 0-0.
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WISE, E.; COX, B.; JAROŠ, J.; TREEBY, B. Representing arbitrary acoustic source and sensor distributions in Fourier collocation methods. Journal of the Acoustical Society of America, 2019, vol. 146, no. 1, p. 278-288. ISSN: 1520-8524.
Detail

JAROŠ, J.; TREEBY, B.: k-Wave-fluid-cuda-v1.3; CUDA implementation of the k-Wave Toolbox version 1.3. http://www.k-wave.org. URL: http://www.k-wave.org. (software)
Detail

JAROŠ, J.; TREEBY, B.; KUKLIŠ, F.; COX, B.: k-Wave-fluid-omp-v1.3; C++ implementation of the k-Wave Toolbox version 1.3. http://www.k-wave.org. URL: http://www.k-wave.org. (software)
Detail

BUDISKÝ, J.; TREEBY, B.; JAROŠ, J.: k-Wave-afp-omp-v1.3; C++ implementation of acoustic field calculation in k-Wave 1.3. http://www.k-wave.org/download.php. URL: http://www.k-wave.org/download.php. (software)
Detail

JAROŠ, J.; TREEBY, B.; COX, B.: k-Wave-fluid-omp-v1.2; C++ implementation of the k-Wave Toolbox version 1.2. http://www.k-wave.org. URL: http://www.k-wave.org. (software)
Detail

JAROŠ, J.; TREEBY, B.: k-Wave-fluid-cuda-v1.2; CUDA implementation of the k-Wave Toolbox version 1.2. http://www.k-wave.org. URL: http://www.k-wave.org. (software)
Detail