Detail předmětu

Biopolymers Properties and Applications

FCH-MAA_BPAAk. rok: 2017/2018

Introduction about biomaterial. Biopolymers (extraction from different sources, characterization. Relation between extraction process and chemical/physical properties of biopolymers. Chemical modification of biopolymers to obtain different properties/different shapes of materials. The applications of the biopolymers in different areas (medical, environmental, textile, pharmaceutics and tissue engineering applications).

Výsledky učení předmětu

Students will improve their knowledge about the biopolymers: Extraction from different sources, characterizations and chemical modifications of biopolymers. Medical and environmental applications of biomaterials.

Prerekvizity

Basic knowledge of organic technology.

Doporučená nebo povinná literatura

Farzana Parveen, Recent Advances in Biopolymers, Elsevier, 2016, 281 (EN)
Vijay Kumar Thakur, Amar Singh Singha, Surface Modification of Biopolymers, Wiley, 2015, 448 (EN)
Alen Walton (Auth.), biopolymers, Elsevier Science,1973,610 (EN)
Gerald O. Aspinall (Auth.), Polysaccharides, Pergamon Press, 1970,242 (EN)
Jean-Michel Mérillon (eds.), Polysaccharides: Bioactivity and Biotechnology, Springer International Publishing,2015,2241 Springer International Publishing,2015,2241 • Jean-Michel Mérillon (eds.), Polysaccharides: Bioactivity and Biotechnology, Springer International Publishing,2015,2241 (EN)
Robert H. Marchessault, François Ravenelle, and Xiao Xia Zhu (Eds.), ACS Symposium Volume 934; Polysaccharides for Drug Delivery and Pharmaceutical Applications, American Chemical Society,2006,354 (EN)

Plánované vzdělávací činnosti a výukové metody

90 % face-to-face, 10 % distance learning

Způsob a kritéria hodnocení

Written test /oral examination/activity participation in lectures (70/20/10)

Jazyk výuky

angličtina

Osnovy výuky

Lecture 1: Introduction about biopolymers such as cellulose/oxycellulose, starch, chitin, dextrin, chitosan, hyaluronic acid, alginate, chitin-glucan complex, pectin, etc.... and their classifications depend on the following parameters.
 Depend on functionality (amino, carboxylic, hydroxyl, thiol, acetamide, etc….).
 Classification depend on structure (mono, di, branched, etc….).
 Depend applications such as biomedical and environmental purposes.
Lecture 2: Different extraction process of biopolymers:
 Chemically (using different chemical treatment),
 Enzymatically (using different enzymes as glucanase, cellulose, hyaluronidase),
 Mechanically (thermal/mechanical treatment).
Lecture 3: Characterization of biopolymers by different techniques and confirmation the structure by measure:
 Degree of polymerization, degree of deaceytlayion/acetylation, carboxylation, thiolation, oxidation,
 Molecular weight calculation,
 Degree of substitution on the linear or branched chains.
Lecture 4: Chemical modifications of by biopolymers:
 Amidation, esterification, graft copolymerization,
 Quaternization of biopolymers, alkylation, oxidation,
 Photo/chemical/physical cross-linking of the surface of biopolymers like chitin, chitosan, hyaluronic acids, alginate, cellulose, chitosan-glucan complex, silk fibroin, carrageenan to generate new different chemical/physical properties
Lecture 5: Preparation of different forms of biopolymers like:
 Membranes, films, fibers/ fabrics, hydrogel, powders,
 3D structure using freeze thawing, freeze-drying, precipitation,
 Casting, wet/electrospinning techniques.
Lecture 6: The medical uses of biopolymers as:
 Healing/dressing wound, cell carrier,
 Antibacterial agents and for bone/cartilage regenerations,
 Environmental application epically for waste water treatments and removing all hazard metals/organic substance.
Lecture 7: Uses of biomaterial (native/modified) in preparation/synthetization of:
 Different metal/metal oxide nanoparticles as reducing/ stabilizing/capping agents such as,
 Silver nanoparticles,
 Gold nanoparticles and zinc oxide nanoparticles,
 Titanium oxide nanoparticles and nanohydroxy apatite and their applications.
Lecture 8: The mechanisms of interactions between metal/metal oxide nanoparticles and biomaterials (native/modified):
 Stabilizing the metal/metal oxide nanoparticles
 reduction of metal/metal oxide nanoparticles using biopolymers such as cellulose/oxy-cellulose, starch, chitin, dextrin, chitosan, hyaluronic acid, alginate, chitin-glucan complex, pectin
 Prevent the aggregation and agglomeration of metal nanoparticles and,
 Preparation of nanocomposite materials.
Lecture 9: The environmental applications of biopolymers:
 Uses of biopolymers such as chitin, chitosan, cyclodextrin, cellulose and their derivatives on metals and organic material removal,
 Uses of biopolymer nanocomposite on wastewater treatments,
 biopolymer smart coating and sensors
Lecture 10: General overview of biopolymers and implantation process (internal and external applications of biopolymers).
 Biodegradable biopolymers based scaffold for bone tissue engineering,
 Biodegradable polymers based scaffold for cartilage tissue engineering,
 Biodegradable polymers based sheets for skin tissue regeneration.
Lecture 11: The chemical modification between biomaterials (native/modified) with;
 Synthetic polymers (poly-carbolactone, polyvinyl alcohol, polyethylene oxide….),
 Proteins (collagen, peptides) and their applications.

Cíl

The main aim of the course is to improve the background of the students how to use the natural sources (animal/non animal) in order to obtain biopolymers and usage in different sectors of our life (medicine, agriculture, pharmaceutics, textile, drug delivery, etc……).

Zařazení předmětu ve studijních plánech

  • Program DKCP_CHM_4 doktorský

    obor DKCO_CHM_4 , 1. ročník, zimní semestr, 0 kreditů, volitelný

  • Program DPCP_CHM_4 doktorský

    obor DPCO_CHM_4 , 1. ročník, zimní semestr, 0 kreditů, volitelný

  • Program DPAP_CHM_4 doktorský

    obor DPAO_CHM_4 , 1. ročník, zimní semestr, 0 kreditů, volitelný

  • Program DKAP_CHM_4 doktorský

    obor DKAO_CHM_4 , 1. ročník, zimní semestr, 0 kreditů, volitelný

  • Program DPCP_MCH_4 doktorský

    obor DPCO_MCH , 1. ročník, zimní semestr, 0 kreditů, volitelný

  • Program DKCP_MCH_4 doktorský

    obor DKCO_MCH , 1. ročník, zimní semestr, 0 kreditů, volitelný

  • Program NKCP_CHM magisterský navazující

    obor NKCO_CHM , 1. ročník, letní semestr, 0 kreditů, volitelný

  • Program NPCP_CHM magisterský navazující

    obor NPCO_CHM , 1. ročník, letní semestr, 0 kreditů, volitelný

  • Program NPCP_CHM_INT magisterský navazující

    obor NPCO_CHM , 1. ročník, letní semestr, 0 kreditů, volitelný

  • Program NKCP_CHM magisterský navazující

    obor NKCO_CHM , 2. ročník, letní semestr, 0 kreditů, volitelný

  • Program NPCP_CHM magisterský navazující

    obor NPCO_CHM , 2. ročník, letní semestr, 0 kreditů, volitelný

Typ (způsob) výuky

 

Přednáška

26 hod., nepovinná

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