Detail publikace

Can we improve the therapy of Clostridium difficile infection in elderly patients?

Bielakova, K Fernandova, E Matejovska-Kubesova, H Weber, P Prudius, D Bednar, J

Originální název

Can we improve the therapy of Clostridium difficile infection in elderly patients?

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

Clostridium difficile infection (CDI) is becoming a serious problem predominantly in geriatric patients, who are a significant risk group. The goal of this study was to evaluate the risk factors for mortality in CDI patients and to construct a binary logistic regression model that describes the probability of mortality in geriatric patients suffering from CDI. In this retrospective study, we evaluated a group of 235 patients over 65 years of age with confirmed diagnoses of CDI, hospitalized at the Department of Internal Medicine, Geriatrics and General Practice, Brno, from January 2008 to December 2013. The examined group comprised 148 women (63 %) and 87 men (37 %). For the diagnosis of CDI, confirmation of A and B toxins in the patients' stool or an autopsy confirmation was crucial. The impact of antibiotic therapy on the increased incidence of CDI was clearly confirmed in our study group when examining patients' histories. Other risk factors included cerebrovascular disease, dementia, the presence of pressure ulcers, and immobility. Our new model consisted of a combination of the following parameters: the number of antibiotics used (from patients' history), nutritional status (Mini Nutritional Assessment short-form test), presence of pressure ulcers, and occurrence of fever.

Klíčová slova

Clostridium difficile; Geriatric patient; Antibiotic therapy; Pseudomebranous colitis; Binary logistic regression model

Autoři

Bielakova, K; Fernandova, E; Matejovska-Kubesova, H; Weber, P; Prudius, D; Bednar, J

Vydáno

1. 8. 2016

Nakladatel

SPRINGER WIEN

Místo

WIEN, AUSTRIA

ISSN

0043-5325

Periodikum

WIENER KLINISCHE WOCHENSCHRIFT

Ročník

128

Číslo

15-16

Stát

Rakouská republika

Strany od

592

Strany do

598

Strany počet

7

URL

http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=1&SID=N2BUl2cSrhFp7VIrdwT&page=1&doc=5

BibTex

@article{BUT131475,
  author="Bielakova, K and Fernandova, E and Matejovska-Kubesova, H and Weber, P and Prudius, D and Bednar, J",
  title="Can we improve the therapy of Clostridium difficile infection in elderly patients?",
  journal="WIENER KLINISCHE WOCHENSCHRIFT",
  year="2016",
  volume="128",
  number="15-16",
  pages="592--598",
  doi="10.1007/s00508-016-1056-z",
  issn="0043-5325",
  url="http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=1&SID=N2BUl2cSrhFp7VIrdwT&page=1&doc=5"
}