Detail publikace

Similarity analysis of primary and secondary structures of metallothioneins

Originální název

Similarity analysis of primary and secondary structures of metallothioneins

Anglický název

Similarity analysis of primary and secondary structures of metallothioneins

Jazyk

en

Originální abstrakt

Metallothioneins (MTs) are small cysteine-rich proteins that are involved in many diverse biological processes, which are interesting especially due to their influence on therapy of cancer. The primary structures of MTs from different organisms are various despite they have the same purpose - a transport of metal ions in organisms. Every single mutation in amino acid sequences can have a drastic effect to secondary structures thereby on MTs function. This study presents dependence of diversity of primary and secondary structures on function of MTs.

Anglický abstrakt

Metallothioneins (MTs) are small cysteine-rich proteins that are involved in many diverse biological processes, which are interesting especially due to their influence on therapy of cancer. The primary structures of MTs from different organisms are various despite they have the same purpose - a transport of metal ions in organisms. Every single mutation in amino acid sequences can have a drastic effect to secondary structures thereby on MTs function. This study presents dependence of diversity of primary and secondary structures on function of MTs.

BibTex


@inproceedings{BUT34568,
  author="Helena {Škutková} and Ivo {Provazník} and René {Kizek}",
  title="Similarity analysis of primary and secondary structures of metallothioneins",
  annote="Metallothioneins (MTs) are small cysteine-rich proteins that are involved in many diverse biological processes, which are interesting especially due to their influence on therapy of cancer. The primary structures of MTs from different organisms are various despite they have the same purpose - a transport of metal ions in organisms.  Every single mutation in amino acid sequences can have a drastic effect to secondary structures thereby on MTs function. This study presents dependence of diversity of primary and secondary structures on function of MTs.",
  address="IEEE",
  booktitle="The 10th IEEE International Conference on Information Technology and Applications in Biomedicine: Emerging Technologies for Patient Specific Healthcare",
  chapter="34568",
  howpublished="electronic, physical medium",
  institution="IEEE",
  year="2010",
  month="november",
  pages="1--4",
  publisher="IEEE",
  type="conference paper"
}