Detail publikace

Antimicrobial activity of selected plant extracts and its possibility to effect human health

Marie Vysoká, V.L. Mazzarello, G. Delogu, I. Márová

Originální název

Antimicrobial activity of selected plant extracts and its possibility to effect human health

Typ

abstrakt

Jazyk

angličtina

Originální abstrakt

This study was designed to evaluate the antimicrobial activity and cytotoxicity of selected plant extracts and its possibility to effect human health. Herbal medicines are used widely because of their potent therapeutic efficacy, antioxidant activities and no side effects. In this study, tested samples of herbs were prepared as water extracts and essential oils. All extracts were prepared from dry samples of Curcumin, Euterpe oleracea, Origanum vulgare, Panax Ginseng, Syzygium aromaticum and Zingiber officinale. Antimicrobial effect was tested on Staphylococcus aureus, Candida glabrata and Escherichia coli. Cytotoxicity was tested in by colorimetric MTT test on keratinocytes HaCaT and B16F1 and also on other cell lines, e.g. Caco-2, Raji. In all extracts was detected concentration dependent antimicrobial effect. Apoptosis, the cell’s natural mechanism for death, is a promising target for anticancer therapy. The hallmarks of cancer are present in all cancer cells regardless of the cause or type; these include uncontrolled growth, angiogenesis and apoptosis evasion. The prevention of cancer is one of the main functions of apoptosis. In this study was tested the apoptotic effects of selected plant extracts of Raji cell lines.

Klíčová slova

antimicrobial activity, Caco - 2, Raji, Mtt test, apoptosis

Autoři

Marie Vysoká, V.L. Mazzarello, G. Delogu, I. Márová

Vydáno

26. 2. 2021

Nakladatel

Biotechnology & Biotechnological Equipment, Volume 35, Issue sup1 (2021)

ISSN

1314-3530

Periodikum

Biotechnology and Biotechnological Equipment

Číslo

35(1)

Stát

Spojené království Velké Británie a Severního Irska

Strany od

25

Strany do

26

Strany počet

1

URL

BibTex

@misc{BUT169841,
  author="Marie {Vysoká} and Ivana {Márová}",
  title="Antimicrobial activity of selected plant extracts and its possibility to effect human health",
  year="2021",
  journal="Biotechnology and Biotechnological Equipment",
  number="35(1)",
  pages="25--26",
  publisher="Biotechnology & Biotechnological Equipment, Volume 35, Issue sup1 (2021)",
  doi="10.1080/13102818.2020.1871545",
  issn="1314-3530",
  url="https://eurobiotech2020.eu/",
  note="abstract"
}