Detail publikace

Blind Source Separation of Retinal Pulsatile Patterns in Optic Nerve Head Video-Recordings

LABOUNKOVÁ, I. LABOUNEK, R. NESTRAŠIL, I. ODSTRČILÍK, J. TORNOW, R. KOLÁŘ, R.

Originální název

Blind Source Separation of Retinal Pulsatile Patterns in Optic Nerve Head Video-Recordings

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

Dynamic optical imaging of retinal hemodynamics is a rapidly evolving technique in vision and eye-disease research. Video-recording, which may be readily accessible and affordable, captures several distinct functional phenomena such as the spontaneous venous pulsations (SVP) of central vein or local arterial blood supply etc. These phenomena display specific dynamic patterns that have been detected using manual or semi-automated methods. We propose a pioneering concept in retina video-imaging using blind source separation (BSS) serving as an automated localizer of distinct areas with temporally synchronized hemodynamics. The feasibility of BSS techniques (such as spatial principal component analysis and spatial independent component analysis) and K-means based post-processing method were successfully tested on the monocular and binocular video-ophthalmoscopic (VO) recordings of optic nerve head (ONH) in healthy subjects. BSSs automatically detected three spatially distinct reproducible areas, i.e. SVP, optic cup pulsations (OCP) that included areas of larger vessels in the nasal part of ONH, and “other” pulsations (OP). The K-means post-processing reduced a spike noise from the patterns’ dynamics while high linear dependence between the non-filtered and post-processed signals was preserved. Although the dynamics of all patterns were heart rate related, the morphology analysis demonstrated significant phase shifts between SVP and OCP, and between SVP and OP. In addition, we detected low frequency oscillations that may represent respiratory-induced effects in time-courses of the VO recordings.

Klíčová slova

Blind Source Separation; ICA; Independent Component Analysis; Optic Nerve Head; PCA; Principal Component Analysis; Retina; Video-ophthalmoscopy; Spontaneous Venous Pulsations

Autoři

LABOUNKOVÁ, I.; LABOUNEK, R.; NESTRAŠIL, I.; ODSTRČILÍK, J.; TORNOW, R.; KOLÁŘ, R.

Vydáno

1. 3. 2021

Nakladatel

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC, 445 HOES LANE, PISCATAWAY, USA, NJ, 08855-4141

Místo

USA

ISSN

0278-0062

Periodikum

IEEE TRANSACTIONS ON MEDICAL IMAGING

Ročník

40

Číslo

3

Stát

Spojené státy americké

Strany od

852

Strany do

864

Strany počet

13

URL

https://ieeexplore.ieee.org/document/9269462

BibTex

@article{BUT166086,
  author="Ivana {Labounková} and René {Labounek} and Igor {Nestrašil} and Jan {Odstrčilík} and Ralf-Peter {Tornow} and Radim {Kolář}",
  title="Blind Source Separation of Retinal Pulsatile Patterns in Optic Nerve Head Video-Recordings",
  journal="IEEE TRANSACTIONS ON MEDICAL IMAGING",
  year="2021",
  volume="40",
  number="3",
  pages="852--864",
  doi="10.1109/TMI.2020.3039917",
  issn="0278-0062",
  url="https://ieeexplore.ieee.org/document/9269462"
}