Detail publikace

A COMPACT MEMS CHIP FOR A RAPID AND HIGHLY ACCURATE PICOLITER CALORIMETRY

NI, S. ZHU, H. NEUŽIL, P. YOBAS, L.

Originální název

A COMPACT MEMS CHIP FOR A RAPID AND HIGHLY ACCURATE PICOLITER CALORIMETRY

Anglický název

A COMPACT MEMS CHIP FOR A RAPID AND HIGHLY ACCURATE PICOLITER CALORIMETRY

Jazyk

en

Originální abstrakt

We introduce a compact MEMS-based microcalorimeter (mu C) for rapid ultrasmall-volume sample analysis. The chip features a time constant of 4 ms, with the possibility of achieving high scanning rate and sensitivity without noticeably distorting the thermograms. We demonstrated the chip performance in differential scanning calorimeter (DSC) mode and measured the melting temperature (T-m) of bovine serum albumin (BSA) at 75 K.min(-1), one of the fastest scan rate reported. The measured melting point of 77.4 degrees C is practically identical to that measured by a conventional MEMS-based DSC. Our system exhibits an unprecedented accuracy at such a high scanning rate having the capability of perfomring a flash DSC analysis for a liquid phase sample.

Anglický abstrakt

We introduce a compact MEMS-based microcalorimeter (mu C) for rapid ultrasmall-volume sample analysis. The chip features a time constant of 4 ms, with the possibility of achieving high scanning rate and sensitivity without noticeably distorting the thermograms. We demonstrated the chip performance in differential scanning calorimeter (DSC) mode and measured the melting temperature (T-m) of bovine serum albumin (BSA) at 75 K.min(-1), one of the fastest scan rate reported. The measured melting point of 77.4 degrees C is practically identical to that measured by a conventional MEMS-based DSC. Our system exhibits an unprecedented accuracy at such a high scanning rate having the capability of perfomring a flash DSC analysis for a liquid phase sample.

Dokumenty

BibTex


@inproceedings{BUT165707,
  author="Pavel {Neužil}",
  title="A COMPACT MEMS CHIP FOR A RAPID AND HIGHLY ACCURATE PICOLITER CALORIMETRY",
  annote="We introduce a compact MEMS-based microcalorimeter (mu C) for rapid ultrasmall-volume sample analysis. The chip features a time constant of 4 ms, with the possibility of achieving high scanning rate and sensitivity without noticeably distorting the thermograms. We demonstrated the chip performance in differential scanning calorimeter (DSC) mode and measured the melting temperature (T-m) of bovine serum albumin (BSA) at 75 K.min(-1), one of the fastest scan rate reported. The measured melting point of 77.4 degrees C is practically identical to that measured by a conventional MEMS-based DSC. Our system exhibits an unprecedented accuracy at such a high scanning rate having the capability of perfomring a flash DSC analysis for a liquid phase sample.",
  address="IEEE",
  booktitle="IEEE International Conference on Micro Electro Mechanical Systems",
  chapter="165707",
  doi="10.1109/MEMS46641.2020.9056359",
  howpublished="print",
  institution="IEEE",
  year="2020",
  month="april",
  pages="1006--1009",
  publisher="IEEE",
  type="conference paper"
}