Detail publikace

ISOLATION OF ARGININE USING MAGHEMITE PARTICLES

CERNEI, N. KOPEL, P. HORKÝ, P. ZÍTKA, O. ADAM, V.

Originální název

ISOLATION OF ARGININE USING MAGHEMITE PARTICLES

Typ

článek ve sborníku ve WoS nebo Scopus

Jazyk

angličtina

Originální abstrakt

In this paper, we report the optimal conditions for the isolation of amino acid arginine from different types of matrix, such as blood, plasma or tissue and their characterization using ion-exchange liquid chromatography with VIS detector. Paramagnetic microparticles able to isolate and immobilize amino acid arginine were prepared and used to preconcentrate arginine for subsequent analysis on ion-exchange liquid chromatography with VIS detector. Commercially available Dowex was covered by maghemite nanoparticles and the composite showed excellent binding and superparamagnetic properties. It was found that the paramagnetic microparticles were able to bind specifically amino acid arginine. Therefore, these paramagnetic microparticles have potential for better isolation of arginine and in future can use for application as a platform of delivery system.

Klíčová slova

Ion exchange chromatography; maghemite microparticles; amino acids; arginine

Autoři

CERNEI, N.; KOPEL, P.; HORKÝ, P.; ZÍTKA, O.; ADAM, V.

Vydáno

1. 3. 2019

ISBN

978-80-87294-89-5

Kniha

NANOCON 2018

Strany od

210

Strany do

213

Strany počet

4

BibTex

@inproceedings{BUT163397,
  author="Natalia Vladimirovna {Cernei} and Pavel {Kopel} and Pavel {Horký} and Ondřej {Zítka} and Vojtěch {Adam}",
  title="ISOLATION OF ARGININE USING MAGHEMITE PARTICLES
",
  booktitle="NANOCON 2018",
  year="2019",
  pages="210--213",
  isbn="978-80-87294-89-5"
}