Detail publikace

Bioactive TiCaPCON-coated PCL nanofibers as a promising material for bone tissue engineering

MANAKHOV, A. PERMYAKOVA, E. ERSHOV, S. SHEVEYKO, A. KOVALSKII, A. POLČÁK, J. ZHITNYAK, I. GLOUSHANKOVA, N. ZAJÍČKOVÁ, L. SHTANSKY, D.

Originální název

Bioactive TiCaPCON-coated PCL nanofibers as a promising material for bone tissue engineering

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

This work deals with the deposition of bioactive TiCaPCON films onto biodegradable polycaprolactone (PCL) nanofibers using magnetron sputtering for bone tissue engineering. Low melting point of PCL nanofibers requires a careful tuning of processing parameters in order to achieve high film quality and avoid substrate degradation. SEM and XPS analyses showed that, with the magnetron current of 2 A, the TiCaPCON films deposited onto PCL nanofibers and Si wafers exhibit similar chemical states hereby indicating that the nanofiber structure is not affected by the deposition process. In vitro biological tests indicated that the osteoblasts adhesion and proliferation as well the ALP activity can be significantly improved by depositing the TiCaPCON film onto PCL. The reported findings suggest a new strategy for the preparation of biodegradable polymer-based biomaterials for bone tissue engineering.

Klíčová slova

PCL; TiCaPCON; Nanofibers; Magnetron sputtering; XPS; Osteoblast

Autoři

MANAKHOV, A.; PERMYAKOVA, E.; ERSHOV, S.; SHEVEYKO, A.; KOVALSKII, A.; POLČÁK, J.; ZHITNYAK, I.; GLOUSHANKOVA, N.; ZAJÍČKOVÁ, L.; SHTANSKY, D.

Vydáno

15. 6. 2019

Nakladatel

ELSEVIER SCIENCE BV

Místo

AMSTERDAM

ISSN

0169-4332

Periodikum

Applied Surface Science

Ročník

479

Číslo

1

Stát

Nizozemsko

Strany od

796

Strany do

802

Strany počet

7

URL

https://www.sciencedirect.com/science/article/pii/S0169433219305057?via%3Dihub

BibTex

@article{BUT161050,
  author="Anton {Manakhov} and Elizaveta {Permyakova} and Sergey {Ershov} and A.N. {Sheveyko} and Andrey {Kovalskii} and Josef {Polčák} and I.Y. {Zhitnyak} and Natalia A. {Gloushankova} and Lenka {Zajíčková} and Dmitry V. {Shtansky}",
  title="Bioactive TiCaPCON-coated PCL nanofibers as a promising material for bone tissue engineering",
  journal="Applied Surface Science",
  year="2019",
  volume="479",
  number="1",
  pages="796--802",
  doi="10.1016/j.apsusc.2019.02.163",
  issn="0169-4332",
  url="https://www.sciencedirect.com/science/article/pii/S0169433219305057?via%3Dihub"
}