Detail publikace

Mathematical modeling of the IV-administered drug concentration level

Originální název

Mathematical modeling of the IV-administered drug concentration level

Anglický název

Mathematical modeling of the IV-administered drug concentration level

Jazyk

en

Originální abstrakt

The paper considers models of the IV-administration of a drug with differential equations describing the drug concentration in the body. An explanation is given of the fluctuating and irregular plasma concentration patterns of some drugs observed during intravenous infusion. A new mathematical model is offered of drug intravenous administration with respect to the existence of one or more peaks or undulations of the plasma concentration curve. An illustrative example is considered for certain values of the drug infusion rate and its elimination rate.

Anglický abstrakt

The paper considers models of the IV-administration of a drug with differential equations describing the drug concentration in the body. An explanation is given of the fluctuating and irregular plasma concentration patterns of some drugs observed during intravenous infusion. A new mathematical model is offered of drug intravenous administration with respect to the existence of one or more peaks or undulations of the plasma concentration curve. An illustrative example is considered for certain values of the drug infusion rate and its elimination rate.

BibTex


@inproceedings{BUT150429,
  author="Miroslava {Růžičková} and Josef {Diblík} and Gabriela {Vážanová}",
  title="Mathematical modeling of the IV-administered drug concentration level",
  annote="The paper considers models of the IV-administration of a drug with differential equations describing the drug concentration in the body. An explanation is given of the fluctuating and irregular plasma concentration patterns of some drugs observed during intravenous infusion. A new mathematical model is offered of drug intravenous administration with respect to the existence of one or more peaks or undulations of the plasma concentration curve. An illustrative example is considered for certain values of the drug infusion rate and its elimination rate.",
  address="American Institute of Physics",
  booktitle="INTERNATIONAL CONFERENCE OF NUMERICAL ANALYSIS AND APPLIED MATHEMATICS (ICNAAM 2017)",
  chapter="150429",
  doi="10.1063/1.5044026",
  howpublished="online",
  institution="American Institute of Physics",
  year="2018",
  month="july",
  pages="430011-1--4300011-4",
  publisher="American Institute of Physics",
  type="conference paper"
}