Detail publikace

High resolution gold printed electrodes for cell culture monitoring by OECT transistors

Originální název

High resolution gold printed electrodes for cell culture monitoring by OECT transistors

Anglický název

High resolution gold printed electrodes for cell culture monitoring by OECT transistors

Jazyk

en

Originální abstrakt

The organic electrochemical transistor (OECT) has a potential for development of innovative biomedical devices. The cultivation of cells in vitro is potentially powerful tool for investigation of drug interaction with the organism for treatment and toxicity testing. In our work, microplate with multi-electrode array of OECTs fabricated by ink-jet technique with gold printed interdigital electrodes and screen printed or spin coated PEDOT:PSS was developed. The high-resolution gold printed electrode up to 55 µm channel length was achieved. The transconductance above 6 mS and time constant 20 ms (frequency up to 50 Hz) were achieved (see Fig. 1). The biocompatibility of 6 commercially available PEDOT:PSS inks and 4 representative semiconductors for utilization in the OECT were tested with 3T3 fibroblasts and murine cardiomyocytes. The developed sensor platforms were used for electrical stimulation and synchronization of beating cardiomyocytes.

Anglický abstrakt

The organic electrochemical transistor (OECT) has a potential for development of innovative biomedical devices. The cultivation of cells in vitro is potentially powerful tool for investigation of drug interaction with the organism for treatment and toxicity testing. In our work, microplate with multi-electrode array of OECTs fabricated by ink-jet technique with gold printed interdigital electrodes and screen printed or spin coated PEDOT:PSS was developed. The high-resolution gold printed electrode up to 55 µm channel length was achieved. The transconductance above 6 mS and time constant 20 ms (frequency up to 50 Hz) were achieved (see Fig. 1). The biocompatibility of 6 commercially available PEDOT:PSS inks and 4 representative semiconductors for utilization in the OECT were tested with 3T3 fibroblasts and murine cardiomyocytes. The developed sensor platforms were used for electrical stimulation and synchronization of beating cardiomyocytes.

BibTex


@misc{BUT149004,
  author="Stanislav {Stříteský} and Lukáš {Omasta} and Šárka {Tumová} and Ota {Salyk} and Martin {Vala} and Martin {Weiter}",
  title="High resolution gold printed electrodes for cell culture monitoring by OECT transistors",
  annote="The organic electrochemical transistor (OECT) has a potential for development of innovative biomedical devices. The cultivation of cells in vitro is potentially powerful tool for investigation of drug interaction with the organism for treatment and toxicity testing. 
In our work, microplate with multi-electrode array of OECTs fabricated by ink-jet technique with gold printed interdigital electrodes and screen printed or spin coated PEDOT:PSS was developed. The high-resolution gold printed electrode up to 55 µm channel length was achieved. The transconductance above 6 mS and time constant 20 ms (frequency up to 50 Hz) were achieved (see Fig. 1). The biocompatibility of 6 commercially available PEDOT:PSS inks and 4 representative semiconductors for utilization in the OECT were tested with 3T3 fibroblasts and murine cardiomyocytes. The developed sensor platforms were used for electrical stimulation and synchronization of beating cardiomyocytes.
",
  chapter="149004",
  howpublished="online",
  year="2018",
  month="march",
  pages="85--85",
  type="abstract"
}