Detail publikace

Effects of Voltage Sensitive Dye di-4-ANEPPS on Guinea Pig Myocardium

Originální název

Effects of Voltage Sensitive Dye di-4-ANEPPS on Guinea Pig Myocardium

Anglický název

Effects of Voltage Sensitive Dye di-4-ANEPPS on Guinea Pig Myocardium

Jazyk

en

Originální abstrakt

Voltage-sensitive dyes have been employed to record monophasic action potentials (MAPs) in a variety of heart preparations with results comparable to classical microelectrode method. However, still little data are available on the response of the heart muscle to the loading with the dye. One of the most consistently used dyes – di-4-ANEPPS - is employed in our laboratory to record MAPs from isolated guinea pig hearts. It is of great importance to prove that loading of the heart muscle does not result in pharmacological or toxic effects to the preparation, since the experiments are of long duration, e.g. to prove the viability and quality of the heart at the beginning of the experiment.

Anglický abstrakt

Voltage-sensitive dyes have been employed to record monophasic action potentials (MAPs) in a variety of heart preparations with results comparable to classical microelectrode method. However, still little data are available on the response of the heart muscle to the loading with the dye. One of the most consistently used dyes – di-4-ANEPPS - is employed in our laboratory to record MAPs from isolated guinea pig hearts. It is of great importance to prove that loading of the heart muscle does not result in pharmacological or toxic effects to the preparation, since the experiments are of long duration, e.g. to prove the viability and quality of the heart at the beginning of the experiment.

BibTex


@inproceedings{BUT14703,
  author="Marie {Nováková} and Ivo {Provazník} and Jana {Kolářová} and Milan {Blaha}",
  title="Effects of Voltage Sensitive Dye di-4-ANEPPS on Guinea Pig Myocardium",
  annote="Voltage-sensitive dyes have been employed to record monophasic action potentials (MAPs) in a variety of heart preparations with results comparable to classical microelectrode method. However, still little data are available on the response of the heart muscle to the loading with the dye. One of the most consistently used dyes – di-4-ANEPPS - is employed in our laboratory to record MAPs from isolated guinea pig hearts. It is of great importance to prove that loading of the heart muscle does not result in pharmacological or toxic effects to the preparation, since the experiments are of long duration, e.g. to prove the viability and quality of the heart at the beginning of the experiment.",
  address="IFBME",
  booktitle="Proceedings of EMBEC 2005",
  chapter="14703",
  institution="IFBME",
  year="2005",
  month="september",
  pages="1",
  publisher="IFBME",
  type="conference paper"
}