Detail publikace

PREPARATION AND ANTIMICROBIAL ACTIVITY OF NUCLEOBASE-CONJUGATED CdTe / ZnSe CORE / SHELL QUANTUM DOTS

MOULICK, A. ČÍHALOVÁ, K. MILOSAVLJEVIĆ, V. KOPEL, P. ADAM, V. HEGER, Z. KIZEK, R.

Originální název

PREPARATION AND ANTIMICROBIAL ACTIVITY OF NUCLEOBASE-CONJUGATED CdTe / ZnSe CORE / SHELL QUANTUM DOTS

Typ

článek ve sborníku ve WoS nebo Scopus

Jazyk

angličtina

Originální abstrakt

Inorganic nanomaterials have large specific surface area and high bioactivity which made them promising alternatives to the traditional organic antimicrobial agents that are extremely irritant and toxic. In the present report, CdTe/ZnSe core/shell quantum dots (QDs) were conjugated with different nucleobases and their antibacterial activity against Escherichia coli was investigated. The CdTe/ZnSe core/shell QDs were synthesized in a green way or environment-friendly way using water as a solvent instead of organic solvents. They were successfully conjugated with different nucleobases and were characterized using fluorescence and absorbance spectrophotometry and dynamic light scattering techniques. The antimicrobial activity of all the samples along with control (bare QDs) was checked on E. coli, a commonly used bacterial model species in microbiology research. Almost all nucleobases showed good antibacterial activity comparing to control probably forming excess ROS which can disturb different metabolisms in bacterial cell. Guanine showed the best result among all other nucleobases.

Klíčová slova

Quantum dots; nucleobases; antibacterial activity

Autoři

MOULICK, A.; ČÍHALOVÁ, K.; MILOSAVLJEVIĆ, V.; KOPEL, P.; ADAM, V.; HEGER, Z.; KIZEK, R.

Vydáno

16. 10. 2015

ISBN

978-80-87294-63-5

Kniha

NANOCON 2015

Strany od

537

Strany do

541

Strany počet

5

BibTex

@inproceedings{BUT143521,
  author="Amitava {Moulick} and Kristýna {Číhalová} and Vedran {Milosavljević} and Pavel {Kopel} and Vojtěch {Adam} and Zbyněk {Heger} and René {Kizek}",
  title="PREPARATION AND ANTIMICROBIAL ACTIVITY OF NUCLEOBASE-CONJUGATED CdTe / ZnSe CORE / SHELL QUANTUM DOTS",
  booktitle="NANOCON 2015",
  year="2015",
  pages="537--541",
  isbn="978-80-87294-63-5"
}